High contrast breast cancer biomarker imaging using upconverting nanoparticles

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dc.contributor.authorSekar, Sanathana K. V.
dc.contributor.authorMa, Hui
dc.contributor.authorKomolibus, Katarzyna
dc.contributor.authorDumlupinar, Gokhan
dc.contributor.authorKrawczyk, Krzysztof
dc.contributor.authorMickert, Matthias
dc.contributor.authorAndersson-Engels, Stefan
dc.date.accessioned2022-10-05T14:06:00Z
dc.date.available2022-10-05T14:06:00Z
dc.date.issued2022-04
dc.date.updated2022-10-05T14:02:47Z
dc.description.abstractBreast cancer is a leading cause of death in women and has scope for improvement in treatment stratification. We report the use of high contrast UCNP staining to distinguish different levels of HER2 expression in HER2 analyte control and HER2-positive breast cancer tissue biopsies. A contrast of 40 was found as compared to the negative control and 25 as compared to conventional DAB staining.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleidJM1A.4en
dc.identifier.citationSekar, S.K.V., Ma, H., Komolibus, K., Dumlupinar, G., Krawczyk, K., Mickert, M. and Andersson-Engels, S. (2022) ‘High contrast breast cancer biomarker imaging using upconverting nanoparticles’, in Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), 24-27 April. https://doi.org/10.1364/TRANSLATIONAL.2022.JM1A.4en
dc.identifier.doi10.1364/TRANSLATIONAL.2022.JM1A.4en
dc.identifier.endpage2en
dc.identifier.isbn978-1-957171-03-6
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/13744
dc.language.isoenen
dc.publisherOptica Publishing Groupen
dc.relation.ispartofBiophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN)
dc.relation.urihttps://doi.org/10.1364/TRANSLATIONAL.2022.JM1A.4
dc.rights© 2022 The Author(s). Published by Optical Publishing Groupen
dc.subjectBreast canceren
dc.subjectHigh contrast UCNP stainingen
dc.subjectBreast cancer tissue biopsiesen
dc.subjectHER2 expressionen
dc.subjectEmissionen
dc.subjectFourier transformsen
dc.subjectImage processingen
dc.subjectMicroscopyen
dc.subjectNanoparticlesen
dc.subjectTissueen
dc.titleHigh contrast breast cancer biomarker imaging using upconverting nanoparticlesen
dc.typeConference itemen
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