C-reactive protein and radiographic findings of lower respiratory tract infection in infants.
dc.contributor.author | Twomey, Maria | |
dc.contributor.author | Fleming, Hannah | |
dc.contributor.author | Moloney, Fiachra | |
dc.contributor.author | Murphy, Kevin P. | |
dc.contributor.author | Crush, Lee | |
dc.contributor.author | O'Neill, Siobhán B. | |
dc.contributor.author | Flanagan, Oisin | |
dc.contributor.author | Bogue, Conor O. | |
dc.contributor.author | O'Connor, Owen J. | |
dc.contributor.author | Maher, Michael M. | |
dc.date.accessioned | 2018-04-26T10:41:23Z | |
dc.date.available | 2018-04-26T10:41:23Z | |
dc.date.issued | 2017-04-28 | |
dc.date.updated | 2018-04-23T16:19:08Z | |
dc.description.abstract | AIM: To evaluate the association between C-reactive protein (CRP) and radiological evidence of lower respiratory tract infection (LRTI) in infants. METHODS: All patients aged less than 4 years who presented with suspected lower respiratory tract infection, who received a peri-presentation chest radiograph and CRP blood measurement over an 18-mo period were included in the study. Age, gender, source of referral, CRP, white cell count, neutrophil count along with the patients’ symptoms and radiologist’s report were recorded. RESULTS: Three hundred and eleven patients met the inclusion criteria. Abnormal chest radiographs were more common in patients with elevated CRP levels (P < 0.01). Radiologic signs of LRTI were identified in 73.7% of chest radiographs when a patient had a CRP level between 50-99 mg/L. CRP levels were a better predictor of positive chest radiograph findings for those aged greater than I year compared to those 1 year or less. CONCLUSION: CRP may be used in patients with suspected LRTI diagnosis to select those who are likely to have positive findings on chest radiograph, thus reducing unnecessary chest radiographs. Core tip: Abnormal chest radiograph findings are significantly more common in patients with elevated C-reactive protein (CRP) levels. Young children are most likely to have abnormal chest radiograph findings if they have all three of the following; a CRP level of 50-99 mg/L, respiratory symptoms and if they are aged greater than 1 year. | en |
dc.description.status | Peer reviewed | en |
dc.description.version | Published Version | en |
dc.format.mimetype | application/pdf | en |
dc.identifier.citation | Twomey, M., Fleming, H., Moloney, F., Murphy, K. P., Crush, L., O’Neill, S. B., Flanagan, O., James, K., Bogue, C., O’Connor, O. J. and Maher, M. M. (2017) ‘C-reactive protein and radiographic findings of lower respiratory tract infection in infants’, World Journal of Radiology: WJR, 9(4) pp. 206-211. doi:10.4329/wjr.v9.i4.206 | en |
dc.identifier.doi | 10.4329/wjr.v9.i4.206 | |
dc.identifier.endpage | 211 | en |
dc.identifier.issn | 1949-8470 | |
dc.identifier.issued | 4 | en |
dc.identifier.journaltitle | Journal of Medical Imaging and Radiation Oncology | en |
dc.identifier.startpage | 206 | en |
dc.identifier.uri | https://hdl.handle.net/10468/5881 | |
dc.identifier.volume | 9 | en |
dc.language.iso | en | en |
dc.publisher | Baishideng Publishing Group | en |
dc.rights | © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | en |
dc.subject | Chest radiograph | en |
dc.subject | C-reactive protein | en |
dc.subject | Chest infection | en |
dc.subject | Respiratory infection | en |
dc.subject | Pediatric | en |
dc.title | C-reactive protein and radiographic findings of lower respiratory tract infection in infants. | en |
dc.type | Article (peer-reviewed) | en |
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