Looking beyond the terrestrial: The potential of seaweed derived bioactives to treat non-communicable diseases

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dc.contributor.authorCollins, Kenneth G.
dc.contributor.authorFitzgerald, Gerald F.
dc.contributor.authorStanton, Catherine
dc.contributor.authorRoss, R. Paul
dc.contributor.funderMarine Instituteen
dc.contributor.funderDepartment of Agriculture, Food and the Marineen
dc.contributor.funderTeagascen
dc.date.accessioned2019-11-26T10:52:44Z
dc.date.available2019-11-26T10:52:44Z
dc.date.issued2016-03-18
dc.description.abstractSeaweeds are a large and diverse group of marine organisms that are commonly found in the maritime regions of the world. They are an excellent source of biologically active secondary metabolites and have been shown to exhibit a wide range of therapeutic properties, including anti-cancer, anti-oxidant, anti-inflammatory and anti-diabetic activities. Several Asian cultures have a strong tradition of using different varieties of seaweed extensively in cooking as well as in herbal medicines preparations. As such, seaweeds have been used to treat a wide variety of health conditions such as cancer, digestive problems, and renal disorders. Today, increasing numbers of people are adopting a “westernised lifestyle” characterised by low levels of physical exercise and excessive calorific and saturated fat intake. This has led to an increase in numbers of chronic Non-communicable diseases (NCDs) such as cancer, cardiovascular disease, and diabetes mellitus, being reported. Recently, NCDs have replaced communicable infectious diseases as the number one cause of human mortality. Current medical treatments for NCDs rely mainly on drugs that have been obtained from the terrestrial regions of the world, with the oceans and seas remaining largely an untapped reservoir for exploration. This review focuses on the potential of using seaweed derived bioactives including polysaccharides, antioxidants and fatty acids, amongst others, to treat chronic NCDs such as cancer, cardiovascular disease and diabetes mellitus.en
dc.description.sponsorshipNational Development Plan 2007–2013 (No. MFFRI/07/01 and 13F511 (PREMARA))en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid60en
dc.identifier.citationCollins, K. G., Fitzgerald, G. F., Stanton, C. and Ross, R. P. (2016) 'Looking Beyond the Terrestrial: The Potential of Seaweed Derived Bioactives to Treat Non-Communicable Diseases', Marine Drugs, 14(3), 60 (31pp) doi: 10.3390/md14030060en
dc.identifier.doi10.3390/md14030060en
dc.identifier.eissn1660-3397
dc.identifier.endpage31en
dc.identifier.issued3en
dc.identifier.journaltitleMarine Drugsen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/9244
dc.identifier.volume14en
dc.language.isoenen
dc.publisherMDPIen
dc.rights© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectSeaweeden
dc.subjectBioactivesen
dc.subjectNon-communicable diseaseen
dc.subjectCanceren
dc.subjectDiabetesen
dc.subjectCardiovascular diseaseen
dc.subjectFucoidanen
dc.subjectShort-chain fatty acidsen
dc.subjectPrebioticsen
dc.titleLooking beyond the terrestrial: The potential of seaweed derived bioactives to treat non-communicable diseasesen
dc.typeArticle (peer-reviewed)en
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