Effects of feeding Bt MON810 maize to sows during first gestation and lactation on maternal and offspring health indicators

dc.contributor.authorBuzoianu, Stefan G.
dc.contributor.authorGardiner, Gillian E.
dc.contributor.authorRea, Mary C.
dc.contributor.authorO'Donovan, Orla
dc.contributor.authorRoss, R. Paul
dc.contributor.authorLawlor, Peadar G.
dc.contributor.authorWalsh, Maria C.
dc.contributor.funderSeventh Framework Programmeen
dc.contributor.funderTeagascen
dc.date.accessioned2017-11-20T10:39:43Z
dc.date.available2017-11-20T10:39:43Z
dc.date.issued2012-07-04
dc.date.updated2017-11-16T10:25:02Z
dc.description.abstractA total of twenty-four sows and their offspring were used in a 20-week study to investigate the effects of feeding GM maize on maternal and offspring health. Sows were fed diets containing GM or non-GM maize from service to the end of lactation. GM maize-fed sows were heavier on day 56 of gestation (P< 0·05). Offspring from sows fed GM maize tended to be lighter at weaning (P= 0·08). Sows fed GM maize tended to have decreased serum total protein (P= 0·08), and increased serum creatinine (P< 0·05) and γ-glutamyltransferase activity (P= 0·07) on day 28 of lactation. Serum urea tended to be decreased on day 110 of gestation in GM maize-fed sows (P= 0·10) and in offspring at birth (P= 0·08). Both platelet count (P= 0·07) and mean cell Hb concentration (MCHC; P= 0·05) were decreased on day 110 of gestation in GM maize-fed sows; however, MCHC tended to be increased in offspring at birth (P= 0·08). There was a minimal effect of feeding GM maize to sows during gestation and lactation on maternal and offspring serum biochemistry and haematology at birth and body weight at weaning.en
dc.description.sponsorshipTeagasc (Walsh Fellowship)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationWalsh, M. C., Buzoianu, S. G., Gardiner, G. E., Rea, M. C., O'Donovan, O., Ross, R. P. and Lawlor, P. G. (2012) 'Effects of feeding Bt MON810 maize to sows during first gestation and lactation on maternal and offspring health indicators', British Journal of Nutrition, 109(5), pp. 873-881. doi:10.1017/S0007114512002607en
dc.identifier.doi10.1017/S0007114512002607
dc.identifier.endpage881en
dc.identifier.issn0007-1145
dc.identifier.issued5en
dc.identifier.journaltitleBritish Journal of Nutritionen
dc.identifier.startpage873en
dc.identifier.urihttps://hdl.handle.net/10468/5066
dc.identifier.volume109en
dc.language.isoenen
dc.publisherCambridge University Pressen
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/211820/EU/Biomarkers for post market monitoring of short and long-term effects of genetically modified organisms (GMOs) on animal and human health/GMSAFOODen
dc.rights© 2012, the Authors. Published by Cambridge University Press (CUP) on behalf of the Nutrition Society.en
dc.subjectMaizeen
dc.subjectCry1Aben
dc.subject1 epidopteran-active crystalline proteinen
dc.subjectCross-generational effectsen
dc.subjectGM fooden
dc.subjectSafetyen
dc.titleEffects of feeding Bt MON810 maize to sows during first gestation and lactation on maternal and offspring health indicatorsen
dc.typeArticle (peer-reviewed)en
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