Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction

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dc.contributor.authorLaffan, J.
dc.contributor.authorGao, H.
dc.contributor.authorStreet, A.
dc.contributor.authorCoughlan, J.J.
dc.contributor.authorArmstrong, R.
dc.contributor.authorMaree, A.
dc.contributor.authorBlake, G.
dc.contributor.authorKearney, P.
dc.contributor.authorCrowley, J.
dc.contributor.authorKiernan, T.J.
dc.contributor.authorMcCreery, C.
dc.contributor.authorAleong, G.
dc.contributor.authorPeace, A.
dc.contributor.authorKennedy, M.
dc.contributor.authorByrne, R.A.
dc.date.accessioned2026-04-28T15:50:04Z
dc.date.available2026-04-28T15:50:04Z
dc.date.issued2026-03-31
dc.description© 2026, the Author(s) (or their employer(s). Re- use permitted under CC BY-NC. No commercial re- use. See rights and permissions. Published by BMJ Group.
dc.description.abstractBackground: Time to reperfusion is a predictor of long-term outcomes in ST-segment elevation myocardial infarction (STEMI). Timely primary percutaneous coronary intervention (PCI) is the preferred strategy recommended by guidelines. Fibrinolysis is recommended in patients in whom timely primary PCI is not feasible, though concerns persist about underutilisation of this approach. We examined long-term survival outcomes in STEMI patients according to treatment strategy received in a national STEMI registry in Ireland. Methods: This was an observational, nationwide, population-based study. We identified all STEMI cases from January 2013 to March 2018. After exclusion of patients with missing data, we divided patients into three groups as per reperfusion strategy—fibrinolysis, delayed primary PCI (>120 min of diagnosis) and timely primary PCI (en
dc.format.extent7
dc.format.extent831272
dc.identifier.articleide003886
dc.identifier.authororcidLaffan, J.
dc.identifier.authororcidGao, H.
dc.identifier.authororcidStreet, A.
dc.identifier.authororcidCoughlan, J.J.
dc.identifier.authororcidArmstrong, R.
dc.identifier.authororcidMaree, A.
dc.identifier.authororcidBlake, G.
dc.identifier.authororcidKearney, P.§0000-0001-9599-3540
dc.identifier.authororcidCrowley, J.
dc.identifier.authororcidKiernan, T.J.
dc.identifier.authororcidMcCreery, C.
dc.identifier.authororcidAleong, G.
dc.identifier.authororcidPeace, A.
dc.identifier.authororcidKennedy, M.§0000-0001-6894-6044
dc.identifier.authororcidByrne, R.A.
dc.identifier.citationLaffan, J, Gao, H, Street, A, Coughlan, J J, Armstrong, R, Maree, A, Blake, G, Kearney, P, Crowley, J, Kiernan, T J, McCreery, C, Aleong, G, Peace, A, Kennedy, M & Byrne, R A 2026, 'Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction', Open Heart, vol. 13, no. 1, e003886, pp. 1-7. https://doi.org/10.1136/openhrt-2025-003886
dc.identifier.doi10.1136/openhrt-2025-003886
dc.identifier.endpage7
dc.identifier.issn2398-595X
dc.identifier.issued1
dc.identifier.journaltitleOpen Heart
dc.identifier.otherRIS: urn:4429FA287E9E54289B1FE0348AA969EF
dc.identifier.otherORCID: /0000-0001-6894-6044/work/225078160
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/18707
dc.identifier.urlhttps://www.scopus.com/pages/publications/105036155781
dc.identifier.volume13
dc.language.isoeng
dc.rightscc_by_nc
dc.subjectAcute Coronary Syndrome
dc.subjectPrimary PCI
dc.subjectQuality of health care
dc.subjectSTEMI
dc.subjectThrombolysis
dc.subject[BEES]
dc.titleOutcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarctionen
dc.typeArticle (Peer reviewed)
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