Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction
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Date
2026-03-31
Authors
Laffan, J.
Gao, H.
Street, A.
Coughlan, J.J.
Armstrong, R.
Maree, A.
Blake, G.
Kearney, P.
Crowley, J.
Kiernan, T.J.
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Volume Title
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Published Version
Abstract
Background: Time to reperfusion is a predictor of long-term outcomes in ST-segment elevation myocardial infarction (STEMI). Timely primary percutaneous coronary intervention (PCI) is the preferred strategy recommended by guidelines. Fibrinolysis is recommended in patients in whom timely primary PCI is not feasible, though concerns persist about underutilisation of this approach. We examined long-term survival outcomes in STEMI patients according to treatment strategy received in a national STEMI registry in Ireland. Methods: This was an observational, nationwide, population-based study. We identified all STEMI cases from January 2013 to March 2018. After exclusion of patients with missing data, we divided patients into three groups as per reperfusion strategy—fibrinolysis, delayed primary PCI (>120 min of diagnosis) and timely primary PCI (
Description
© 2026, the Author(s) (or their employer(s). Re- use permitted under CC BY-NC. No commercial re- use. See rights and permissions. Published by BMJ Group.
Keywords
Acute Coronary Syndrome , Primary PCI , Quality of health care , STEMI , Thrombolysis , [BEES]
Citation
Laffan, J, Gao, H, Street, A, Coughlan, J J, Armstrong, R, Maree, A, Blake, G, Kearney, P, Crowley, J, Kiernan, T J, McCreery, C, Aleong, G, Peace, A, Kennedy, M & Byrne, R A 2026, 'Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction', Open Heart, vol. 13, no. 1, e003886, pp. 1-7. https://doi.org/10.1136/openhrt-2025-003886
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cc_by_nc