Comparative genomic analyses of Lactobacillus rhamnosus isolated from Chinese subjects

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dc.contributor.authorHuang, Danen
dc.contributor.authorYang, Boen
dc.contributor.authorChen, Yangen
dc.contributor.authorStanton, Catherineen
dc.contributor.authorRoss, R. Paulen
dc.contributor.authorZhao, Jianxinen
dc.contributor.authorZhang, Haoen
dc.contributor.authorChen, Weien
dc.contributor.funderNational Natural Science Foundation of Chinaen
dc.contributor.funderNational First-Class Discipline Program of Food Science and Technologyen
dc.contributor.funderCollaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Provinceen
dc.date.accessioned2023-10-18T09:10:32Z
dc.date.available2023-10-18T09:10:32Z
dc.date.issued2020-06-27en
dc.description.abstractLactobacillus rhamnosus has been found in many niches, including human intestine, vagina, mouth and dairy products. To intensively investigate the genomic diversity of this species, draft genomes of 70 L. rhamnosus strains isolated from different Chinese subjects were sequenced and further investigated. The pan-genome of L. rhamnosus was open. And gene-trait matching (GTM) was done to explore the carbohydrate utilization ability and antibiotic resistance, and to establish a pattern of gene existence/absence and growth/absence. There were no significant correlations between genetic diversity of the strains and the age or region of the donors. The current results extend the understanding of L. rhamnosus, which could be used as a reference for subsequent research as well as mining and application of the species.en
dc.description.sponsorshipNational Natural Science Foundation of China (Nos. 31771953, 31820103010); National First-Class Discipline Program of Food Science and Technology (JUFSTR20180102)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid100659en
dc.identifier.citationHuang, D., Yang, B., Chen, Y., Stanton, C., Ross, R. P., Zhao, J., Zhang, H. and Chen, W. (2020) 'Comparative genomic analyses of Lactobacillus rhamnosus isolated from Chinese subjects', Food Bioscience, 36, 100659 (13pp). doi: 10.1016/j.fbio.2020.100659en
dc.identifier.doi10.1016/j.fbio.2020.100659en
dc.identifier.eissn2212-4306en
dc.identifier.endpage13en
dc.identifier.issn2212-4292en
dc.identifier.journaltitleFood Bioscienceen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/15129
dc.identifier.volume36en
dc.language.isoenen
dc.publisherElsevier Ltd.en
dc.rights© 2020, Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC BY-NC-ND 4.0 license.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectLactobacillus rhamnosusen
dc.subjectComparative genomicsen
dc.subjectCarbohydrate utilizationen
dc.subjectAntibiotics resistanceen
dc.titleComparative genomic analyses of Lactobacillus rhamnosus isolated from Chinese subjectsen
dc.typeArticle (peer-reviewed)en
oaire.citation.volume36en
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