Improvements in clinical outcomes in children with cystic fibrosis aged six and 16 years

Show simple item record Finn, Bryan P. Millar, Sean R. Cronin, K. Crowley, J. Dunne, S. Jennings, R. Keating, E. Murphy, C. O’Donovan, D. Shanahan, P. Short, C. Mullane, D. Ní Chroinin, M. 2020-12-14T09:19:36Z 2020-12-14T09:19:36Z 2020
dc.identifier.citation Finn, B. P., Millar, S. R., Cronin, K., Crowley, J., Dunne, S., Jennings, R., Keating, E., Murphy, C., O’Donovan, D., Shanahan, P. and Short, C. (2020) 'Improvements in clinical outcomes in children with cystic fibrosis aged six and 16 years', Irish Medical Journal, 113 (7), P119 (6pp). Available at: (Accessed: 14 December 2020) en
dc.identifier.volume 113 en
dc.identifier.issued 7 en
dc.identifier.startpage 1 en
dc.identifier.endpage 6 en
dc.identifier.issn 0332-3102
dc.description.abstract Aims: Our aim was to assess if outcomes for cystic fibrosis (CF) patients at six & sixteen years of age have improved in the last 17 years looking at FEV1, BMI and death. Methods: A retrospective observational study using a prospectively maintained database of CF patients at Cork University Hospital. Results: 84 patients were included in the 16-year-old data and 89 patients were included in the six-year-old data. The mean FEV1 and BMI (16 years) for the 2002-2007 group was 72.9±21.0% and 18.9±2.53 respectively, 2008-2013 group was 75.4±27.2% and 19.8±2.7 and for the 2014-2018 group was 95.2±16.0% and 22.9±4.1. The percentage of patients (16 years) with chronic pseudomonas status was 37.9% (11/30) in the 2002-2007 group, 51.6 % (16/31) in the 2008-2013 group and 4.2% (1/24) in the 2014-2018 group. The relationship between FEV1 and FVC with BMI remained significant in multivariate analysis (P <0.001). The mean FEV1 (six years) for the 2002-2007 group was 90.7±16.1%, 2008-2013 group was 99.3±17.9% and for the 2014-2018 group was 100.9±15.8%. Conclusions: Improvements in FEV1 and BMI aged six and 16 years are notable as well as a significant decline in the number of patients with chronic pseudomonas. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Irish Medical Organisation en
dc.rights © 2020, Irish Medical Organisation. All rights reserved. en
dc.subject Pseudomonas en
dc.subject Cystic fibrosis en
dc.subject CF en
dc.subject FEV1 en
dc.subject BMI en
dc.title Improvements in clinical outcomes in children with cystic fibrosis aged six and 16 years en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Sean Millar, Public Health, University College Cork, Cork, Ireland. T: +353-21- 490-3000 E: en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Irish Medical Journal en
dc.internal.IRISemailaddress en
dc.identifier.articleid P119 en

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