Biocidal inactivation of Lactococcus lactis bacteriophages: efficacy and targets of commonly used sanitizers
Hayes, Stephen; Murphy, James; Mahony, Jennifer; Lugli, Gabriele A.; Ventura, Marco; Noben, Jean-Paul; Franz, Charles M. A. P.; Neve, Horst; Nauta, Arjen; van Sinderen, Douwe
Date:
2017-02-02
Copyright:
© 2017, the Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Citation:
Hayes, S., Murphy, J., Mahony, J., Lugli, G. A., Ventura, M., Noben, J.-P., Franz, C. M. A. P., Neve, H., Nauta, A. and van Sinderen, D. (2017) ‘Biocidal inactivation of Lactococcus lactis bacteriophages: efficacy and targets of commonly used sanitizers’, Frontiers in Microbiology, 8, 107 ((14 pp). doi: 10.3389/fmicb.2017.00107
Abstract:
Lactococcus lactis strains, being intensely used in the dairy industry, are particularly vulnerable to members of the so-called 936 group of phages. Sanitization and disinfection using purpose-made biocidal solutions is a critical step in controlling phage contamination in such dairy processing plants. The susceptibility of 36 936 group phages to biocidal treatments was examined using 14 biocides and commercially available sanitizers. The targets of a number of these biocides were investigated by means of electron microscopic and proteomic analyses. The results from this study highlight significant variations in phage resistance to biocides among 936 phages. Furthermore, rather than possessing resistance to specific biocides or biocide types, biocide-resistant phages tend to possess a broad tolerance to multiple classes of antimicrobial compounds.
Show full item record
Except where otherwise noted, this item's license is described as © 2017, the Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.