Development of a novel single-use microneedle design platform for increased patient compliance

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Date
2017
Authors
Márquez-Graña, C.
Bryan, K.
Vucen, Sonja
O'Sullivan, Caroline
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Volume Title
Publisher
Elsevier B.V.
Published Version
10.1016/j.promfg.2017.09.114
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Abstract
Microneedles (MN) skin patches are novel medical devices in micron scale with a needle array which offers an alternative drug delivery system to conventional methods. MN patches are applied onto the skin reaching the dermal layer where the drug molecules are released at a specific rate. There is a lack of knowledge surrounding some determinant factors required to define an efficient MN application into the user skin. The aim of the project is to determine the optimum application parameters to fabricate a polymeric MN patch and to design a disposable single-use MN applicator with enhanced usability.
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Keywords
Microneedle patches , PLGA , Self-applicator , Atomised spray , Sterilization , State-of-art review
Citation
Márquez-Graña, C., Bryan, K., Vucen, S. and O’Sullivan, C. (2017) 'Development of a novel single-use microneedle design platform for increased patient compliance', Procedia Manufacturing, 13, pp. 1352-1359. doi:10.1016/j.promfg.2017.09.114
Link to publisher’s version
https://www.sciencedirect.com/science/article/pii/S2351978917307497
URI
https://hdl.handle.net/10468/6722
Collections
Pharmacy - Journal Articles
Copyright
© 2017, the Authors. Published by Elsevier B.V. This article is made available under the Creative Commons Attribution-Non Commercial-No Derivs (CC BY-NC-ND) license.