Steroid-induced mental disorders in cancer patients: a systematic review

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dc.contributor.author Ismail, Muhammad Fahmi
dc.contributor.author Lavelle, Clianna
dc.contributor.author Cassidy, Eugene M.
dc.date.accessioned 2018-12-06T10:17:29Z
dc.date.available 2018-12-06T10:17:29Z
dc.date.issued 2017-11-30
dc.identifier.citation Ismail, M. F., Lavelle, C. and Cassidy, E. M. (2017) 'Steroid-induced mental disorders in cancer patients: a systematic review', Future Oncology, 13(29), pp. 2719-2731. doi: 10.2217/fon-2017-0306 en
dc.identifier.volume 13 en
dc.identifier.issued 29 en
dc.identifier.startpage 2719 en
dc.identifier.endpage 2731 en
dc.identifier.issn 1479-6694
dc.identifier.issn 1744-8301
dc.identifier.uri http://hdl.handle.net/10468/7176
dc.identifier.doi 10.2217/fon-2017-0306
dc.description.abstract Corticosteroids are a central part of many cancer treatment regimens. Neuropsychiatric toxicity has complicated their use, including an association with a spectrum of symptoms, from insomnia, cognitive impairment and mood symptoms, to severe mental disorders, including mania, psychosis and severe depression. Although steroid-induced mental disorders were first reported in medicine more than 60 years ago, there is a dearth of evidence available to date on optimal treatment and prevention to guide cancer clinicians. We completed a systematic review of the current evidence for therapeutic and prophylactic interventions of steroid-induced mental disorders in cancer. We searched Medline, Embase and PsycINFO and selected studies related to steroid-induced mental disorder. The studies found were limited to case series and case reports only. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Future Medicine en
dc.relation.uri https://www.futuremedicine.com/doi/abs/10.2217/fon-2017-0306
dc.rights © 2017 Future Medicine. This is the Author’s Accepted Manuscript of a work published in Future Oncology. The version of record is available at https://www.futuremedicine.com/doi/abs/10.2217/fon-2017-0306 en
dc.subject Corticosteroids en
dc.subject Dexamethasone en
dc.subject Glucocorticoids en
dc.subject Hypomania en
dc.subject Mania en
dc.subject Neuropsychiatric adverse effects en
dc.subject Prednisolone en
dc.subject Psychiatric disorder en
dc.subject Psychosissteroid-induced mental disorder en
dc.title Steroid-induced mental disorders in cancer patients: a systematic review en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Eugene Cassidy, Psychiatry and Neurobehavioural Science, University College Cork, Cork, Ireland. T: +353-21-490-3000 E: eugene.cassidy@hse.ie en
dc.internal.availability Full text available en
dc.description.version Accepted Version en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Future Oncology en


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