Impact of BCG vaccination on incidence of tuberculosis disease in southern Ireland
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Published version
Supplementary file 1
Date
2019-05-09
Authors
Sweeney, Eileen
Dahly, Darren L.
Seddiq, Nahed
Corcoran, Gerard
Horgan, Mary
Sadlier, Corinna
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
Published Version
Abstract
Tuberculosis (TB) is the ninth leading cause of death worldwide and the leading cause from a single infectious agent. Bacillus Calmette-Guerin (BCG) is the only licensed vaccine for TB, yet its efficacy remains debated with variations in vaccine sub-strains, policies, and practices observed across the world. Three BCG vaccination policies were implemented across adjoining regions in the South West of Ireland from 1972; neonatal vaccination (vaccinated Region-A), vaccination of children aged 10–12 years (vaccinated Region-B) and no vaccination (unvaccinated Region-C). The aim of this study is to examine the impact of different BCG vaccination policies on incidence of TB disease in the South of Ireland over a 13-year period.
Description
Keywords
Bacille Camille-Guerin (BCG) , Mycobacterium tuberculosis (MTB) , Vaccines
Citation
Sweeney, E., Dahly, D., Seddiq, N., Corcoran, G., Horgan, M. and Sadlier, C. (2019) 'Impact of BCG vaccination on incidence of tuberculosis disease in southern Ireland'. BMC infectious diseases, 19(1), 397. (5pp). DOI:10.1186/s12879-019-4026-z