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The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort
John Wiley & Sons, Inc.
Introduction: Hypertensive Disorders of Pregnancy are common and may result in increased maternal and neonatal morbidity and mortality. Multiple pregnancies confer an increased risk of development of a hypertensive disorder of pregnancy. The purpose of this study was to examine a large cohort of women delivering a multiple pregnancy in a single large tertiary unit, and to evaluate the implications of hypertensive disorders of pregnancy on both maternal and perinatal outcomes. Material and methods: Retrospective study of all twin pregnancies delivered at Cork University Maternity Hospital, Ireland over a 9‐year period (2009–2017). The twin pregnancies were divided according to the presence or absence of hypertensive disorder of pregnancy and the two groups compared. Results: Maternal age >40 years, nulliparity, conception through use of a donor oocyte, and presence of obstetric cholestasis are all risk factors for the development of Hypertensive Disorders of Pregnancy in women with a multiple pregnancy. When a hypertensive disorder complicates a twin pregnancy, it increases the incidence of iatrogenic late prematurity & neonatal hypoglycaemia. Conclusions: This study is informative for clinicians caring for women with a multiple pregnancy with its relevant data on perinatal outcomes following a diagnosis of hypertensive disorder in pregnancy.
Gestational hypertension , Hypertensive disorder of pregnancy , Multiple pregnancy , Twin pregnancy , Pre-eclampsia
Hayes-Ryan, D., Meaney, S., Hodnett, A., Geisler, M. and O'Donoghue, K. (2019) 'The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort', Acta Obstetricia et Gynecologica Scandinavica. doi: 10.1111/aogs.13774
© 2019, Nordic Federation of Societies of Obstetrics and Gynecology. Published by John Wiley & Sons Inc. This is the peer reviewed version of the following article: Hayes-Ryan, D., Meaney, S., Hodnett, A., Geisler, M. and O'Donoghue, K. (2019) 'The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort', Acta Obstetricia et Gynecologica Scandinavica, doi: 10.1111/aogs.13774, which has been published in final form at https://doi.org/10.1111/aogs.13774. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.