A brief guide to studying fear in developing rodents: important considerations and common pitfalls.

Simple item page
dc.contributor.authorCowan, Caitlin S. M.
dc.contributor.authorRichardson, Rick
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderAustralian Research Councilen
dc.contributor.funderNational Health and Medical Research Councilen
dc.date.accessioned2019-02-06T16:07:44Z
dc.date.available2019-02-06T16:07:44Z
dc.date.issued2018-04-26
dc.date.updated2019-02-05T16:21:59Z
dc.description.abstractDevelopment is a time of rapid change that sets the pathway to adult functioning across all aspects of physical and mental health. Developmental studies can therefore offer insight into the unique needs of individuals at different stages of normal development as well as the etiology of various disease states. The aim of this overview is to provide an introduction to the practical implementation of developmental studies in rats and mice, with an emphasis on the study of learned fear. We first discuss how developmental factors may influence experimental outcomes for any study. This is followed by a discussion of methodological issues to consider when conducting studies of developing rodents, highlighting examples from the literature on learned fear. Throughout, we offer some recommendations to guide researchers on best practice in developmental studies.en
dc.description.sponsorshipNational Health and Medical Research Council (APP1031688)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationCowan, C. S. M. and Richardson, R. (2018) 'A Brief Guide to Studying Fear in Developing Rodents: Important Considerations and Common Pitfalls', Current Protocols in Neuroscience, 83(1), e44. doi: 10.1002/cpns.44en
dc.identifier.doi10.1002/cpns.44
dc.identifier.endpagee44en
dc.identifier.issn1934-8576
dc.identifier.issued1en
dc.identifier.journaltitleCurrent Protocols In Neuroscienceen
dc.identifier.startpagee44en
dc.identifier.urihttps://hdl.handle.net/10468/7458
dc.identifier.volume83en
dc.language.isoenen
dc.publisherWileyen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/en
dc.relation.projectinfo:eu-repo/grantAgreement/ARC/Discovery Projects/DP150104835/AU/Discovery Projects - Grant ID: DP150104835/en
dc.relation.urihttps://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpns.44
dc.rightsĀ© 2018 by John Wiley & Sons, Inc. This is the peer reviewed version of the following article: Cowan, C. S. M. and Richardson, R. (2018) 'A Brief Guide to Studying Fear in Developing Rodents: Important Considerations and Common Pitfalls', Current Protocols in Neuroscience, 83(1), pp. e44., which has been published in final form at https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpns.44en
dc.subjectAdolescenceen
dc.subjectAgeā€related changesen
dc.subjectDevelopmenten
dc.subjectFear extinctionen
dc.subjectInfancyen
dc.subjectPavlovian fear conditioningen
dc.subjectRodent studiesen
dc.titleA brief guide to studying fear in developing rodents: important considerations and common pitfalls.en
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
Current_Protocols_manuscript_revision_FINAL-unmarked.docx
Size:
63.1 KB
Format:
Microsoft Word XML
Description:
Author's original
Thumbnail Image
Name:
9070_Current_Protocols_manuscript_revision_FINAL-unmarked.pdf
Size:
131.67 KB
Format:
Adobe Portable Document Format
Description:
Accepted version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
APC Microbiome Ireland - Journal Articles