Sulfoxides: potent co-crystal formers

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dc.contributor.authorEccles, Kevin S.
dc.contributor.authorElcoate, Curtis J.
dc.contributor.authorStokes, Stephen P.
dc.contributor.authorMaguire, Anita R.
dc.contributor.authorLawrence, Simon E.
dc.contributor.funderScience Foundation Irelanden
dc.date.accessioned2014-03-03T10:25:46Z
dc.date.available2014-03-03T10:25:46Z
dc.date.issued2010-10-01
dc.date.updated2013-01-08T11:44:34Z
dc.description.abstractThe design of co-crystals requires knowledge of robust supramol. synthons. The sulfoxide is a potent H bond acceptor and was used as a co-crystal former with a range of NH functional groups, via N-H···O=S H bonds. The NH functional group retains favorable H bond motifs from its own structure in all cases where this is possible, with the sulfoxide interacting in a discrete, capping fashion in four cases and in a bifurcated, bridging fashion in the three other cases presented here. Crystallog. data are given for 7 co-formers, dibenzyl sulfoxide and cyclohexanecarbothioamide.en
dc.description.sponsorshipScience Foundation Ireland under (SRC/B1158 (CE)); Science Foundation Ireland (05/PICA/B802/EC07)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationECCLES, K. S., ELCOATE, C. J., STOKES, S. P., MAGUIRE, A. R. & LAWRENCE, S. E. 2010. Sulfoxides: Potent Co-Crystal Formers. Crystal Growth & Design, 10, 4243-4245.en
dc.identifier.doi10.1021/cg1010192
dc.identifier.endpage4245en
dc.identifier.issn1528-7483
dc.identifier.issued10en
dc.identifier.journaltitleCrystal Growth & Designen
dc.identifier.startpage4243en
dc.identifier.urihttps://hdl.handle.net/10468/1420
dc.identifier.volume10en
dc.language.isoenen
dc.publisherAmerican Chemical Societyen
dc.relation.urihttp://pubs.acs.org/doi/abs/10.1021/cg1010192
dc.rights© 2010, American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Crystal Growth & Design, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/cg1010192en
dc.subjectCrystallography and liquid crystalsen
dc.subject~Chemistry - Journal Articles~en
dc.subject~Pharmacy - Journal Articles~en
dc.subject~Analytical & Biological Chemistry Research Facility - Journal Articles~en
dc.titleSulfoxides: potent co-crystal formersen
dc.typeArticle (peer-reviewed)en
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