Maternal and infant factors that shape neonatal gut colonization by bacteria

Simple item page
dc.contributor.authorO'Neill, Ian J.en
dc.contributor.authorSanchez Gallardo, Rocioen
dc.contributor.authorSaldova, Radkaen
dc.contributor.authorMurphy, Eileen F.en
dc.contributor.authorCotter, Paul D.en
dc.contributor.authorMcAuliffe, Fionnuala M.en
dc.contributor.authorvan Sinderen, Douween
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderHorizon 2020en
dc.contributor.funderAlimentary Healthen
dc.date.accessioned2023-05-10T16:01:50Z
dc.date.available2023-05-10T16:01:50Z
dc.date.issued2020-06-30en
dc.description.abstractIntroduction: Early life is a critical developmental window coinciding with the establishment of a community of neonatal gut microbes which are vitally important for immune development. The composition of this microbial community is affected by multiple factors. Areas covered: The effect of pre-pregnancy and pregnancy maternal health, maternal nutrition, pregnancy disorders such as gestational diabetes, maternal antibiotic usage, delivery mode, infant feeding, and infant antibiotic usage on gut microbial composition are outlined along with the potential impact of associated microbiota differences on infant health. Expert opinion: Recent developments in understanding what shapes our microbiota indicates that the greatest impact on infant gut microbiota composition during the first year of life is seen with the mode of delivery, infant diet, and infant antibiotic usage. Current data is insufficient to fully establish the role of apparently less important factors such as maternal health on microbiota development although their impact is likely smaller. Technological advances will allow for improved understanding of underlying mechanisms by which specific microbes impact on infant health, which in time will enable full appreciation of the role of the gut microbiota in early life development.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationO'Neill, I. J., Sanchez Gallardo, R., Saldova, R., Murphy, E. F., Cotter, P. D., McAuliffe, F. M. and van Sinderen, D. (2020) 'Maternal and infant factors that shape neonatal gut colonization by bacteria', Expert Review of Gastroenterology and Hepatology, 14(8), pp. 651-664. doi: 10.1080/17474124.2020.1784725en
dc.identifier.doi10.1080/17474124.2020.1784725en
dc.identifier.eissn1747-4132en
dc.identifier.endpage664en
dc.identifier.issn1747-4124en
dc.identifier.issued8en
dc.identifier.journaltitleExpert Review of Gastroenterology and Hepatologyen
dc.identifier.startpage651en
dc.identifier.urihttps://hdl.handle.net/10468/14454
dc.identifier.volume14en
dc.language.isoenen
dc.publisherTaylor & Francis Groupen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Spokes Programmeen
dc.relation.projectinfo:eu-repo/grantAgreement/EC/H2020en
dc.rights© 2020, Taylor & Francis. All rights reserved. This is an Accepted Manuscript of an article published by Taylor & Francis on 30 June 2020 in Expert Review of Gastroenterology and Hepatology, available online: https://doi.org/10.1080/17474124.2020.1784725. It is deposited under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectMicrobiomeen
dc.subjectAntibioticsen
dc.subjectBreastmilken
dc.subjectDeliveryen
dc.subjectGut microbiotaen
dc.subjectInfanten
dc.subjectInfant healthen
dc.subjectMicrobiotaen
dc.subjectPregnancyen
dc.titleMaternal and infant factors that shape neonatal gut colonization by bacteriaen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
Review - Early pediatric gut colonization.pdf
Size:
485.59 KB
Format:
Adobe Portable Document Format
Description:
Accepted Version
Download
Thumbnail Image
Name:
Review - Early pediatric gut colonization.docx
Size:
322.75 KB
Format:
Microsoft Word XML
Description:
Author's original accepted version
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
APC Microbiome Ireland - Journal Articles
Microbiology - Journal Articles