Triangular gold nanoparticles modify shell characteristics and increase antioxidant enzyme activities in the clam Ruditapes decussatus
| dc.contributor.author | Abdelhafidh, Khazri | |
| dc.contributor.author | Badreddine, Sellami | |
| dc.contributor.author | Mezni, Amine | |
| dc.contributor.author | Mouhamed, Dellali | |
| dc.contributor.author | Wiem, Saidani | |
| dc.contributor.author | Imen, Bouzidi | |
| dc.contributor.author | Sheehan, David | |
| dc.contributor.author | Mahmoudi, Ezzeddine | |
| dc.contributor.author | Hamouda, Beyrem | |
| dc.contributor.funder | National Institute of Marine Sciences and Technology (INSTM), Tunisia | en |
| dc.contributor.funder | Ministry of Higher Education, and Scientific Research, Tunisia | en |
| dc.contributor.funder | University of Carthage, Tunisia | en |
| dc.date.accessioned | 2018-06-27T11:00:12Z | |
| dc.date.available | 2018-06-27T11:00:12Z | |
| dc.date.issued | 2018-04-07 | |
| dc.date.updated | 2018-06-27T10:42:07Z | |
| dc.description.abstract | Context: Nanoparticles may cause adverse environmental effects but there is limited information on their interactions with marine organisms. Objective: Our aim was to examine the effects of triangular gold nanoparticles (Tr-Au NPs) on the clam, Ruditapes decussatus. Materials and methods: Clams were exposed to Tr-Au1 = 5 µg/L and Tr-Au2 = 10 µg/L for 2 and 7 days. Effects on shell structure were investigated. Superoxide dismutase (SOD), catalase (CAT), glutathione transferase (GST) activities, protein carbonyl levels and malondialdehyde content were used to assess biochemical status. Results: Transmission electron microscopy (TEM) and electron dispersive X-ray microanalysis (EDX) showed that Tr-Au NPs modified shell structure and morphology. Tr-Au NPs size increased forming aggregate particles. Tr-Au NPs increased SOD, CAT and GST activities in gill and digestive gland in a concentration- and time-dependent manner indicating defence against oxidative stress. Enhanced lipid peroxidation and protein carbonyl levels confirmed oxidative stress. Conclusion: Tr-Au NPs cause oxidative stress and affect shell structure of clams. These findings may have relevance to other marine species. | en |
| dc.description.sponsorship | National Institute of Marine Sciences and Technology (INSTM), Tunisia; Ministry of Higher Education, Carthage, Tunisia; Université de Carthage (Laboratory of Environment Biomonitoring, Unit of research 99/UR12-30 and Department of Chemistry, Faculty of Sciences of Bizerte) | en |
| dc.description.status | Peer reviewed | en |
| dc.description.version | Accepted Version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Abdelhafidh, K., Badreddine, S., Mezni, A., Mouhamed, D., Wiem, S., Imen, B., David, S., Mahmoudi, E. and Hamouda, B. (2018) 'Triangular gold nanoparticles modify shell characteristics and increase antioxidant enzyme activities in the clam Ruditapes decussatus', Biomarkers, In Press, doi: 10.1080/1354750X.2018.1463565 | en |
| dc.identifier.doi | 10.1080/1354750X.2018.1463565 | |
| dc.identifier.endpage | 9 | en |
| dc.identifier.issn | 1354-750X | |
| dc.identifier.journaltitle | Biomarkers | en |
| dc.identifier.startpage | 1 | en |
| dc.identifier.uri | https://hdl.handle.net/10468/6380 | |
| dc.language.iso | en | en |
| dc.publisher | Taylor & Francis | en |
| dc.relation.uri | http://www.tandfonline.com/10.1080/1354750X.2018.1463565 | |
| dc.rights | © 2018 Informa UK Limited, trading as Taylor & Francis Group. This is an Accepted Manuscript of an article published by Taylor & Francis in Biomarkers on 19 April 2018, available online: http://www.tandfonline.com/10.1080/1354750X.2018.1463565 | en |
| dc.subject | Oxidative stress | en |
| dc.subject | Biomarkers | en |
| dc.subject | Biomonitoring | en |
| dc.subject | Bivalve | en |
| dc.title | Triangular gold nanoparticles modify shell characteristics and increase antioxidant enzyme activities in the clam Ruditapes decussatus | en |
| dc.type | Article (peer-reviewed) | en |
