Low-dose carotid computed tomography angiography using pure iterative reconstruction

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dc.contributor.authorMoloney, Fiachra
dc.contributor.authorMurphy, Kevin P.
dc.contributor.authorTwomey, Maria
dc.contributor.authorCrish, Lee
dc.contributor.authorCanniffe, Emma M.
dc.contributor.authorMcLaughlin, Patrick D.
dc.contributor.authorMoore, Niamh
dc.contributor.authorO'Keefe, Michael
dc.contributor.authorO'Neill, Siobhán B.
dc.contributor.authorManning, Brian M.
dc.contributor.authorWyse, Gerald
dc.contributor.authorFanning, Noel
dc.contributor.authorO'Connor, Owen J.
dc.contributor.authorMaher, Michael M.
dc.date.accessioned2018-08-16T13:30:22Z
dc.date.available2018-08-16T13:30:22Z
dc.date.issued2016-09
dc.date.updated2018-06-20T16:23:22Z
dc.description.abstractThe aim of this study was to assess if a low-dose carotid computed tomography angiography (CTA) performed with pure iterative reconstruction (IR) is comparable to a conventional dose CTA protocol. Methods: Twenty patients were included. Radiation dose was divided into a low-dose acquisition reconstructed with pure IR and a conventional dose acquisition reconstructed with 40% hybrid IR. Dose, image noise, contrast resolution, spatial resolution, and carotid artery stenosis were measured. Results: Mean effective dose was significantly lower for low-dose than conventional dose studies (1.84 versus 3.71 mSv; P < 0.001). Subjective image noise, contrast resolution, and spatial resolution were significantly higher for the low-dose studies. There was excellent agreement for stenosis grading accuracy between low- and conventional dose studies (Cohen κ = 0.806). Conclusions: A low-dose carotid CTA protocol reconstructed with pure IR is comparable to a conventional dose CTA protocol in terms of image quality and diagnostic accuracy while enabling a dose reduction of 49.6%.en
dc.description.statusPeer revieweden
dc.description.versionSubmitted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMoloney, F., Murphy, K. P., Twomey, M., Crush, L., Canniffe, E. M., McLaughlin, P. D., Moore, N., O'Keeffe, M., O'Neill, S., Manning, B. M., Wyse, G., Fanning, N., O'Connor, O. J. and Maher, M. M. (2016) 'Low-Dose Carotid Computed Tomography Angiography Using Pure Iterative Reconstruction', Journal of Computer Assisted Tomography, 40(5), pp. 833-839. doi: 10.1097/RCT.0000000000000436en
dc.identifier.doi10.1097/RCT.0000000000000436
dc.identifier.endpage839en
dc.identifier.issn0363-8715
dc.identifier.issued5en
dc.identifier.journaltitleJournal of computer assisted tomographyen
dc.identifier.startpage833en
dc.identifier.urihttps://hdl.handle.net/10468/6618
dc.identifier.volume40en
dc.language.isoenen
dc.publisherLippincott, Williams & Wilkinsen
dc.relation.urihttps://journals.lww.com/jcat/Fulltext/2016/09000/Low_Dose_Carotid_Computed_Tomography_Angiography.26.aspx
dc.rights© 2016 Wolters Kluwer Health, Inc. All rights reserved.en
dc.subjectCT angiographyen
dc.subjectMBIRen
dc.subjectpure iterative reconstructionen
dc.subjectAngiographyen
dc.subjectCarotid artery diseaseen
dc.subjectMultidetector CTen
dc.subjectRadiation doseen
dc.subjectStrokeen
dc.subjectPure iterative reconstructionen
dc.titleLow-dose carotid computed tomography angiography using pure iterative reconstructionen
dc.typeArticle (peer-reviewed)en
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