Isolation of Lactobacilli with probiotic properties from the human stomach

Simple item page
dc.contributor.authorRyan, Kieran A.
dc.contributor.authorJayaraman, Thevaraajan
dc.contributor.authorDaly, Paul
dc.contributor.authorCanchaya, Carlos
dc.contributor.authorCurran, Susan
dc.contributor.authorFang, Fang
dc.contributor.authorQuigley, Eamonn M.
dc.contributor.authorO'Toole, Paul W.
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderIrish Research Council for Science Engineering and Technologyen
dc.date.accessioned2010-02-15T10:35:00Z
dc.date.available2010-02-15T10:35:00Z
dc.date.issued2008-10
dc.date.updated2010-02-12T18:14:50Z
dc.description.abstractAims: Recent evidence suggests that the human gastric microbiota is much more diverse than previously thought. The aim of this study was to assess the potential for isolating lactobacilli from the human stomach.Methods and Results: Lactobacilli were selectively cultured from gastric biopsies from 12 patients undergoing routine endoscopy. Lactobacilli were present in four of 12 biopsies. We isolated, in total 10 different strains representing five species (Lactobacillus gasseri, L. fermentum, L. vaginalis, L. reuteri and L. salivarius). The 10 isolates varied greatly in their ability to inhibit the growth of two Gram-positive bacteria and two Gram-negative bacteria. Furthermore, the acid and bile resistance profiles of the 10 isolates spanned a wide range. Conclusions: Five different Lactobacillus species were cultured from human gastric biopsies for the first time. Significance and Impact of the Study: Diverse Lactobacillus species are more prevalent in the human stomach than previously recognized, representing an untapped source of bacteria with beneficial probiotic and/or biotechnological properties.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationRyan, KA, Jayaraman, T, Daly, P, Canchaya, C, Curran, S, Fang, F, Quigley, EM, O'Toole, PW (2008) 'Isolation of Lactobacilli With Probiotic Properties From The Human Stomach'. Letters In Applied Microbiology, 47 (4):269-274.en
dc.identifier.doi10.1111/j.1472-765X.2008.02416.x
dc.identifier.endpage274en
dc.identifier.issn0266-8254
dc.identifier.issn1472-765X
dc.identifier.issued4en
dc.identifier.journaltitleLetters In Applied Microbiologyen
dc.identifier.startpage269en
dc.identifier.urihttps://hdl.handle.net/10468/116
dc.identifier.volume47en
dc.language.isoenen
dc.publisherSociety for Applied Bacteriology; Blackwell Publishingen
dc.rights© 2010 The Society for Applied Microbiology. The definitive version is available at www.blackwell-synergy.comen
dc.rights.uriwww.blackwell-synergy.com
dc.subjectHelicobacter pylorien
dc.subjectBileen
dc.subjectStomachen
dc.subjectAciden
dc.subjectLactobacillien
dc.subjectProbioticsen
dc.subject.lcshLactobacillusen
dc.subject.lcshGastrointestinal system -- Microbiologyen
dc.titleIsolation of Lactobacilli with probiotic properties from the human stomachen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
KAR_isolationAM2008.pdf
Size:
413.43 KB
Format:
Adobe Portable Document Format
Description:
Accepted Version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
4.04 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
APC Microbiome Ireland - Journal Articles
Microbiology - Journal Articles