Cuff-less blood pressure monitoring in a cohort of people with Parkinson's disease

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Crowe, Colum
Sica, Marco
Kenny, Lorna
O'Flynn, Brendan
Mueller, David Scott
Timmons, Suzanne
Barton, John
Tedesco, Salvatore
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Institute of Electrical and Electronics Engineers (IEEE)
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Parkinson's disease is often considered as a “movement disorder”. Nevertheless, People with Parkinson's (PwPD) may also experience other non-motor symptoms, such as abnormalities and alterations in blood pressure (BP). Real-time cuffless BP monitoring may help identify the end-users' overall health state and support clinical decision-making, however most of the studies in the field did not investigate PwPD as a possible cohort of reference. To the best of the authors' knowledge, there are no scientific publications, or commercially available wearable solutions, monitoring BP measurements by means of electrocardiogram (ECG) and/or photoplethysmogram (PPG) in a Parkinsonian cohort. Based on a Random Forest (RF) model and a combination of publicly available data and data collected in lab-settings using a wearable prototype developed at Tyndall National Institute, good performance were achieved on both systolic and diastolic BP measurements with a mean absolute error equal to 7.84±8.12 and 7.51±6.16 mmHg , respectively, for PwPD. As BP disorders are highly prevalent in PwPD, and can mimic dopaminergic deficiency, this work is a step forward in the effective management of motor and non-motor symptoms in this complex cohort of patients.
Cuff-less blood pressure , Blood pressure monitoring , PwPD , Parkinson's , Wearable
Crowe, C., Sica, M., Kenny, L., O'Flynn, B., Mueller, D. S., Timmons, S., Barton, J. and Tedesco, S. (2023) 'Cuff-less blood pressure monitoring in a cohort of people with Parkinson's disease', 2023 IEEE Sensors Applications Symposium (SAS), Ottawa, ON, Canada, 18-20 July, pp. 1-5. doi: 10.1109/SAS58821.2023.10253995
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