Cuff-less blood pressure monitoring in a cohort of people with Parkinson's disease

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dc.contributor.authorCrowe, Columen
dc.contributor.authorSica, Marcoen
dc.contributor.authorKenny, Lornaen
dc.contributor.authorO'Flynn, Brendanen
dc.contributor.authorMueller, David Scotten
dc.contributor.authorTimmons, Suzanneen
dc.contributor.authorBarton, Johnen
dc.contributor.authorTedesco, Salvatoreen
dc.contributor.funderEnterprise Irelanden
dc.contributor.funderAbbVieen
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderEuropean Regional Development Funden
dc.date.accessioned2023-10-31T14:40:29Z
dc.date.available2023-10-31T14:40:29Z
dc.date.issued2023-09-22en
dc.description.abstractParkinson's disease is often considered as a “movement disorder”. Nevertheless, People with Parkinson's (PwPD) may also experience other non-motor symptoms, such as abnormalities and alterations in blood pressure (BP). Real-time cuffless BP monitoring may help identify the end-users' overall health state and support clinical decision-making, however most of the studies in the field did not investigate PwPD as a possible cohort of reference. To the best of the authors' knowledge, there are no scientific publications, or commercially available wearable solutions, monitoring BP measurements by means of electrocardiogram (ECG) and/or photoplethysmogram (PPG) in a Parkinsonian cohort. Based on a Random Forest (RF) model and a combination of publicly available data and data collected in lab-settings using a wearable prototype developed at Tyndall National Institute, good performance were achieved on both systolic and diastolic BP measurements with a mean absolute error equal to 7.84±8.12 and 7.51±6.16 mmHg , respectively, for PwPD. As BP disorders are highly prevalent in PwPD, and can mimic dopaminergic deficiency, this work is a step forward in the effective management of motor and non-motor symptoms in this complex cohort of patients.en
dc.description.sponsorshipEnterprise Ireland and AbbVie (Agreement IP 2017 0625); Science Foundation Ireland (Grant 12/RC/2289-P2-INSIGHT)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationCrowe, C., Sica, M., Kenny, L., O'Flynn, B., Mueller, D. S., Timmons, S., Barton, J. and Tedesco, S. (2023) 'Cuff-less blood pressure monitoring in a cohort of people with Parkinson's disease', 2023 IEEE Sensors Applications Symposium (SAS), Ottawa, ON, Canada, 18-20 July, pp. 1-5. doi: 10.1109/SAS58821.2023.10253995en
dc.identifier.doi10.1109/sas58821.2023.10253995en
dc.identifier.endpage5en
dc.identifier.isbn979-8-3503-2307-8en
dc.identifier.isbn979-8-3503-0098-7en
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/15166
dc.language.isoenen
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.relation.ispartof2023 IEEE Sensors Applications Symposium (SAS), Ottawa, ON, Canada, 18-20 July.en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres Programme::Phase 1/16/RC/3918/IE/Confirm Centre for Smart Manufacturing/en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/13/RC/2077/IE/CONNECT: The Centre for Future Networks & Communications/en
dc.rights© 2023, IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.en
dc.subjectCuff-less blood pressureen
dc.subjectBlood pressure monitoringen
dc.subjectPwPDen
dc.subjectParkinson'sen
dc.subjectWearableen
dc.titleCuff-less blood pressure monitoring in a cohort of people with Parkinson's diseaseen
dc.typeConference itemen
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