International expert panel’s potentially inappropriate prescribing cascades (PIPC) list
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Date
2025-07-31
Authors
Rochon, Paula A.
O’Mahony, Denis
Cherubini, Antonio
Onder, Graziano
Petrovic, Mirko
Dalton, Kieran
McCarthy, Lisa M.
Sternberg, Shelley A.
Zwas, Donna R.
Stall, Nathan M.
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Abstract
Aim: To create a list of potentially inappropriate prescribing cascades (PIPCs) that should be considered when reviewing a patient’s medications. Findings: Through a modified Delphi process, an international expert panel reached consensus on 65 potentially inappropriate prescribing cascades to be included in the final PIPC list. Message: This PIPC list can assist in identifying potentially inappropriate prescribing cascades and help to foster medication safety in older adults.
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© 2025, the Author(s), under exclusive licence to European Geriatric Medicine Society. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
Keywords
Delphi consensus , Older adults , Optimizing drug therapy , Prescribing cascade , [Medicine] , [Pharmacy] , Gerontology , Geriatrics and Gerontology
Citation
Rochon, P A, O’Mahony, D, Cherubini, A, Onder, G, Petrovic, M, Dalton, K, McCarthy, L M, Sternberg, S A, Zwas, D R, Stall, N M, Reppas-Rindlisbacher, C E, van der Velde, N, Hilmer, S N, Wu, W, Li, J, Ly, A & Gurwitz, J H 2025, 'International expert panel’s potentially inappropriate prescribing cascades (PIPC) list', European Geriatric Medicine, vol. 16, no. 5, pp. 1573–1584 . https://doi.org/10.1007/s41999-025-01215-x
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