dc.contributor.author	Phillips, Catherine M.
dc.contributor.author	Dillon, Christina B.
dc.contributor.author	Harrington, Janas M.
dc.contributor.author	McCarthy, Vera J. C.
dc.contributor.author	Kearney, Patricia M.
dc.contributor.author	Fitzgerald, Anthony P.
dc.contributor.author	Perry, Ivan J.
dc.contributor.funder	Health Research Board	en
dc.date.accessioned	2014-03-19T16:04:03Z
dc.date.available	2014-03-19T16:04:03Z
dc.date.issued	2013-10-17
dc.date.updated	2013-11-28T14:29:15Z
dc.description.abstract	Background: There is a current lack of consensus on defining metabolically healthy obesity (MHO). Limited data on dietary and lifestyle factors and MHO exist. The aim of this study is to compare the prevalence, dietary factors and lifestyle behaviours of metabolically healthy and unhealthy obese and non-obese subjects according to different metabolic health criteria. Method: Cross-sectional sample of 1,008 men and 1,039 women aged 45-74 years participated in the study. Participants were classified as obese (BMI ≥30kg/m2) and non-obese (BMI <30kg/m2). Metabolic health status was defined using five existing MH definitions based on a range of cardiometabolic abnormalities. Dietary composition and quality, food pyramid servings, physical activity, alcohol and smoking behaviours were examined. Results: The prevalence of MHO varied considerably between definitions (2.2% to 11.9%), was higher among females and generally increased with age. Agreement between MHO classifications was poor. Among the obese, prevalence of MH was 6.8% to 36.6%. Among the non-obese, prevalence of metabolically unhealthy subjects was 21.8% to 87%. Calorie intake, dietary macronutrient composition, physical activity, alcohol and smoking behaviours were similar between the metabolically healthy and unhealthy regardless of BMI. Greater compliance with food pyramid recommendations and higher dietary quality were positively associated with metabolic health in obese (OR 1.45-1.53 unadjusted model) and non-obese subjects (OR 1.37-1.39 unadjusted model), respectively. Physical activity was associated with MHO defined by insulin resistance (OR 1.87, 95% CI 1.19-2.92, p = 0.006).	en
dc.description.sponsorship	Health Research Board (HRC/2007/13)	en
dc.description.status	Peer reviewed	en
dc.description.version	Published Version	en
dc.format.mimetype	application/pdf	en
dc.identifier.citation	PHILLIPS, C. M., DILLON, C., HARRINGTON, J. M., MCCARTHY, V. J. C., KEARNEY, P. M., FITZGERALD, A. P. & PERRY, I. J. 2013. Defining Metabolically Healthy Obesity: Role of Dietary and Lifestyle Factors. PLoS ONE, 8 (10), e76188. doi:10.1371/journal.pone.0076188	en
dc.identifier.doi	10.1371/journal.pone.0076188
dc.identifier.issn	1932-6203
dc.identifier.issued	10	en
dc.identifier.journaltitle	PLoS One	en
dc.identifier.startpage	e76188	en
dc.identifier.uri	https://hdl.handle.net/10468/1474
dc.identifier.volume	8	en
dc.language.iso	en	en
dc.publisher	Public Library of Science	en
dc.rights	© 2013 Phillips et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited	en
dc.subject	Alcohol consumption	en
dc.subject	Body mass index	en
dc.subject	Carbohydrate metabolism	en
dc.subject	Insulin resistance	en
dc.subject	Metabolic disorders	en
dc.subject	Obesity	en
dc.subject	Vegetables	en
dc.subject	Carbohydrates	en
dc.title	Defining metabolically healthy obesity: role of dietary and lifestyle factors	en
dc.type	Article (peer-reviewed)	en

Defining metabolically healthy obesity: role of dietary and lifestyle factors

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