Management of neonatal hypotension and shock

Thumbnail Image
Schwarz, Christoph E.
Dempsey, Eugene M.
Journal Title
Journal ISSN
Volume Title
Research Projects
Organizational Units
Journal Issue
The current standard approach to manage circulatory insufficiency is inappropriately simple and clear: respond to low blood pressure to achieve higher values. However, the evidence for this is limited affecting all steps within the process: assessment, decision making, therapeutic options, and treatment effects. We have to overcome the â one size fits allâ approach and respect the dynamic physiologic transition from fetal to neonatal life in the context of complex underlying conditions. Caregivers need to individualize their approaches to individual circumstances. This paper will review various clinical scenarios, including managing transitional low blood pressure, to circulatory impairment involving different pathologies such as hypoxia-ischemia and sepsis. We will highlight the current evidence and set potential goals for future development in these areas. We hope to encourage caregivers to question the current standards and to support urgently needed research in this overlooked but crucial field of neonatal intensive care.
Cardiac output , Cardiovascular drugs , Circulatory failure , Hypotension , Neonatal hemodynamics , Newborn , Oxygen balance , Perfusion , Shock , Systemic blood flow
Schwarz, C. E. and Dempsey, E. M. (2020) 'Management of neonatal hypotension and shock', Seminars In Fetal & Neonatal Medicine, 25 (5), 101121 (7pp). doi: 10.1016/j.siny.2020.101121
Link to publisher’s version