Management of neonatal hypotension and shock

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dc.contributor.authorSchwarz, Christoph E.
dc.contributor.authorDempsey, Eugene M.
dc.contributor.funderDeutsche Forschungsgemeinschaften
dc.date.accessioned2022-06-08T14:58:33Z
dc.date.available2022-06-08T14:58:33Z
dc.date.issued2020-01
dc.date.updated2022-06-08T14:41:29Z
dc.description.abstractThe current standard approach to manage circulatory insufficiency is inappropriately simple and clear: respond to low blood pressure to achieve higher values. However, the evidence for this is limited affecting all steps within the process: assessment, decision making, therapeutic options, and treatment effects. We have to overcome the â one size fits allâ approach and respect the dynamic physiologic transition from fetal to neonatal life in the context of complex underlying conditions. Caregivers need to individualize their approaches to individual circumstances. This paper will review various clinical scenarios, including managing transitional low blood pressure, to circulatory impairment involving different pathologies such as hypoxia-ischemia and sepsis. We will highlight the current evidence and set potential goals for future development in these areas. We hope to encourage caregivers to question the current standards and to support urgently needed research in this overlooked but crucial field of neonatal intensive care.en
dc.description.sponsorshipDeutsche Forschungsgemeinschaft (DFG, German Research Foundation, Project number 42053645)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid101121en
dc.identifier.citationSchwarz, C. E. and Dempsey, E. M. (2020) 'Management of neonatal hypotension and shock', Seminars In Fetal & Neonatal Medicine, 25 (5), 101121 (7pp). doi: 10.1016/j.siny.2020.101121en
dc.identifier.doi10.1016/j.siny.2020.101121en
dc.identifier.endpage7en
dc.identifier.issn1744-165X
dc.identifier.issued5en
dc.identifier.journaltitleSeminars In Fetal & Neonatal Medicineen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/13289
dc.identifier.volume25en
dc.language.isoenen
dc.publisherElsevieren
dc.rights© 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Ten
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectCardiac outputen
dc.subjectCardiovascular drugsen
dc.subjectCirculatory failureen
dc.subjectHypotensionen
dc.subjectNeonatal hemodynamicsen
dc.subjectNewbornen
dc.subjectOxygen balanceen
dc.subjectPerfusionen
dc.subjectShocken
dc.subjectSystemic blood flowen
dc.titleManagement of neonatal hypotension and shocken
dc.typeArticle (peer-reviewed)en
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