Interpretation of cerebral oxygenation changes in the preterm infant

dc.contributor.authorGarvey, Aisling A.
dc.contributor.authorKooi, Elisabeth M. W.
dc.contributor.authorSmith, Aisling
dc.contributor.authorDempsey, Eugene M.
dc.contributor.funderSeventh Framework Programme
dc.contributor.funderScience Foundation Ireland
dc.date.accessioned2018-08-29T15:47:28Z
dc.date.available2018-08-29T15:47:28Z
dc.date.issued2018
dc.description.abstractNear-infrared spectroscopy (NIRS) allows for continuous, non-invasive monitoring of end-organ tissue oxygenation. The use of NIRS, cerebral NIRS (cNIRS) in particular, in neonatal care has increased significantly over the last few years. This dynamic monitoring technique provides real-time information on the cerebral and haemodynamic status of the neonate and has the potential to serve as an important adjunct to patient care with some centres routinely utilising cNIRS to aid decision-making at the bedside. cNIRS values may be influenced by many variables, including cardiac, respiratory and metabolic parameters, and therefore it is essential to understand the pathophysiology behind alterations in cNIRS values. Correct interpretation is required to direct appropriate patient-specific interventions. This article aims to assist clinicians in deciphering cNIRS values by providing an overview of potential causes of fluctuations in cNIRS values, illustrated by common clinical scenarios, with particular emphasis on the preterm infant.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid94
dc.identifier.citationGarvey, A., Kooi, E., Smith, A. and Dempsey, E. (2018) 'Interpretation of cerebral oxygenation changes in the preterm infant', Children, 5(7), 94 (16pp). doi: 10.3390/children5070094en
dc.identifier.doi10.3390/children5070094
dc.identifier.endpage16
dc.identifier.issn2227-9067
dc.identifier.issued7
dc.identifier.journaltitleChildrenen
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/6678
dc.identifier.volume5
dc.language.isoenen
dc.publisherMDPI AGen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2272/IE/Irish Centre for Fetal and Neonatal Translational Research (INFANT)/
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::HEALTH/260777/EU/Management of Hypotension In the Preterm Extremely Low Gestational Age Newborn/THE HIP TRIAL
dc.relation.urihttp://www.mdpi.com/2227-9067/5/7/94
dc.rights© 2018, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectNear-infrared spectroscopyen
dc.subjectNIRSen
dc.subjectCerebral oxygenationen
dc.subjectEnd-organ tissue oxygenationen
dc.subjectNeonateen
dc.subjectPretermen
dc.subjectIndividualised patient careen
dc.titleInterpretation of cerebral oxygenation changes in the preterm infanten
dc.typeReviewen
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