EAACI Biologicals Guidelines - Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12-17 years old

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dc.contributor.authorAgache, Ioanaen
dc.contributor.authorAkdis, Cezmien
dc.contributor.authorAkdis, Mubeccelen
dc.contributor.authorBrockow, Knuten
dc.contributor.authorChivato, Tomasen
dc.contributor.authordel Giacco, Stefanoen
dc.contributor.authorEiwegger, Thomasen
dc.contributor.authorEyerich, Kilianen
dc.contributor.authorGiménez-Arnau, Anaen
dc.contributor.authorGutermuth, Janen
dc.contributor.authorGuttman-Yassky, Emmaen
dc.contributor.authorMaurer, Marcusen
dc.contributor.authorOgg, Grahamen
dc.contributor.authorOng, Peck Y.en
dc.contributor.authorO’Mahony, Liamen
dc.contributor.authorSchwarze, Jürgenen
dc.contributor.authorWarner, Amenaen
dc.contributor.authorWerfel, Thomasen
dc.contributor.authorPalomares, Oscaren
dc.contributor.authorJutel, Mareken
dc.date.accessioned2023-04-19T12:12:46Z
dc.date.available2023-04-19T12:53:33Zen
dc.date.available2023-04-19T12:12:46Z
dc.date.issued2021-12-29
dc.date.updated2023-04-19T11:53:36Z
dc.description.abstractChronic spontaneous urticaria (CSU) imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity and insufficient efficacy of classical drugs such as H1R-antihistamines. Better understanding of the mechanisms has enabled a stratified approach to the management of CSU, supporting the use of targeted treatment with omalizumab. However, many practical issues including selection of responders, the definition of response, strategies to enhance the responder rate, the duration of treatment and its regimen (in the clinic or home-based) and its cost-effectiveness still require further clarification. The EAACI Guidelines on the use of omalizumab in CSU follow the GRADE approach in formulating recommendations for each outcome. In addition, future therapeutic approaches and perspectives as well as research priorities are discussed.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Version
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAgache, I., Akdis, C., Akdis, M., Brockow, K., Chivato, T., del Giacco, S., Eiwegger, T., Eyerich, K., Giménez-Arnau, A., Gutermuth, J., Guttman-Yassky, E., Maurer, M., Ogg, G., Ong, P. Y., O’Mahony, L., Schwarze, J., Warner, A., Werfel, T., Palomares, O. and Jutel, M. (2021) 'EAACI Biologicals Guidelines - Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12-17 years old'. Allergy, 77(1), pp. 1-338. doi: 10.1111/all.15030
dc.identifier.doi10.1111/all.15030en
dc.identifier.eissn1398-9995
dc.identifier.endpage338
dc.identifier.issn0105-4538
dc.identifier.issued1
dc.identifier.journaltitleAllergy
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/14393
dc.identifier.volume77
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.
dc.rights© 2021, European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd. This is the accepted version of the following item: Agache, I., Akdis, C., Akdis, M., Brockow, K., Chivato, T., del Giacco, S., Eiwegger, T., Eyerich, K., Giménez-Arnau, A., Gutermuth, J., Guttman-Yassky, E., Maurer, M., Ogg, G., Ong, P. Y., O’Mahony, L., Schwarze, J., Warner, A., Werfel, T., Palomares, O. and Jutel, M. (2021) 'EAACI Biologicals Guidelines - Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12-17 years old'. Allergy, 77(1), pp. 1-338, doi: 10.1111/all.15030, which has been published in final form at: https://doi.org/10.1111/all.15030. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
dc.subjectChronic spontaneous urticaria
dc.subjectGRADE
dc.subjectGuidelines
dc.subjectOmalizumab
dc.titleEAACI Biologicals Guidelines - Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12-17 years olden
dc.typeArticle (peer-reviewed)
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