Finding the needle in the haystack: systematic identification of psychobiotics

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dc.contributor.authorBambury, Aisling
dc.contributor.authorSandhu, Kiran V.
dc.contributor.authorCryan, John F.
dc.contributor.authorDinan, Timothy G.
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderHealth Research Boarden
dc.contributor.funderSeventh Framework Programmeen
dc.contributor.funderEuropean Commissionen
dc.date.accessioned2018-01-09T12:50:08Z
dc.date.available2018-01-09T12:50:08Z
dc.date.issued2017-12-15
dc.date.updated2018-01-09T12:33:05Z
dc.description.abstractThe brain-gut-microbiota axis is increasingly viewed as a novel paradigm in neuroscience with the capacity to generate innovative therapies for patients with psychiatric illnesses. Psychobiotics, defined as live bacteria which when ingested in adequate amounts confer mental health benefits, are increasingly of interest, as pre-clinical trials continue to show promising results. Particularly in stress related, anxiety and depressive disorders, there is potential for psychobiotics to deliver new therapies. The question of which microbes may prove to be the most promising psychobiotic in delivering such therapies at clinical level is of great importance. Here we look at the characteristics of psychobiotics, in an attempt to present an outline, from which the identification of potential new psychobiotics may be possible.en
dc.description.sponsorshipHealth Research Board (Grant Numbers HRA_POR/2011/23 and HRA_POR/2012/32)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBambury, A., Sandhu, K., Cryan, J. F. and Dinan, T. G. 'Finding the needle in the haystack: systematic identification of psychobiotics', British Journal of Pharmacology, In Press, doi: 10.1111/bph.14127en
dc.identifier.doi10.1111/bph.14127
dc.identifier.endpage21en
dc.identifier.issn1476-5381
dc.identifier.journaltitleBritish Journal of Pharmacologyen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/5250
dc.language.isoenen
dc.publisherWileyen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/en
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/613979/EU/Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior./MYNEWGUTen
dc.rights© 2017 The British Pharmacological Society. Published by Wiley. This is the peer reviewed version of the following article: Bambury, A., Sandhu, K., Cryan, J. F., and Dinan, T. G. (2017) Finding the needle in the haystack: systematic identification of psychobiotics. British Journal of Pharmacology, which has been published in final form at http://dx.doi.org/10.1111/bph.14127. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.en
dc.subjectBrain-gut-microbiota axisen
dc.subjectPsychobioticsen
dc.subjectPsychiatric illnessen
dc.subjectNeuroscienceen
dc.subjectStressen
dc.subjectDepressive disordersen
dc.titleFinding the needle in the haystack: systematic identification of psychobioticsen
dc.typeArticle (peer-reviewed)en
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