Attention control comparisons with SLT for people with aphasia following stroke: methodological concerns raised following a systematic review

dc.check.date2019-06-17
dc.check.infoAccess to this article is restricted until 12 months after publication by request of the publisher.en
dc.contributor.authorBrady, Marian C.
dc.contributor.authorGodwin, Jon
dc.contributor.authorKelly, Helen
dc.contributor.authorEnderby, Pam
dc.contributor.authorElders, Andrew
dc.contributor.authorCampbell, Pauline
dc.contributor.funderChief Scientist Officeen
dc.contributor.funderScottish Government Health and Social Care Directorateen
dc.date.accessioned2019-01-22T11:10:41Z
dc.date.available2019-01-22T11:10:41Z
dc.date.issued2018-06-17
dc.date.updated2019-01-22T10:05:11Z
dc.description.abstractObjective: Attention control comparisons in trials of stroke rehabilitation require care to minimize the risk of comparison choice bias. We compared the similarities and differences in SLT and social support control interventions for people with aphasia. Data sources: Trial data from the 2016 Cochrane systematic review of SLT for aphasia after stroke. Methods: Direct and indirect comparisons between SLT, social support and no therapy controls. We double-data extracted intervention details using the template for intervention description and replication. Standardized mean differences and risk ratios (95% confidence intervals (CIs)) were calculated. Results: Seven trials compared SLT with social support (n  =  447). Interventions were matched in format, frequency, intensity, duration and dose. Procedures and materials were often shared across interventions. Social support providers received specialist training and support. Targeted language rehabilitation was only described in therapy interventions. Higher drop-out (P  =  0.005, odds ratio (OR) 0.51, 95% CI 0.32–0.81) and non-adherence to social support interventions (P  <  0.00001, OR 0.18, 95% CI 0.09–0.37) indicated an imbalance in completion rates increasing the risk of control comparison bias. Conclusion: Distinctions between social support and therapy interventions were eroded. Theoretically based language rehabilitation was the remaining difference in therapy interventions. Social support is an important adjunct to formal language rehabilitation. Therapists should continue to enable those close to the person with aphasia to provide tailored communication support, functional language stimulation and opportunities to apply rehabilitation gains. Systematic group differences in completion rates is a design-related risk of bias in outcomes observed.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBrady, M. C., Godwin, J., Kelly, H., Enderby, P., Elders, A. and Campbell, P. (2018) 'Attention control comparisons with SLT for people with aphasia following stroke: methodological concerns raised following a systematic review', Clinical Rehabilitation, 32(10), pp. 1383-1395. doi:10.1177/0269215518780487en
dc.identifier.doi10.1177/0269215518780487
dc.identifier.endpage1395en
dc.identifier.issn0269-2155
dc.identifier.issn1477-0873
dc.identifier.issued10en
dc.identifier.journaltitleClinical Rehabilitationen
dc.identifier.startpage1383en
dc.identifier.urihttps://hdl.handle.net/10468/7337
dc.identifier.volume32en
dc.language.isoenen
dc.publisherSAGE Publicationsen
dc.rights© 2018, the Authors. This is an Accepted Manuscript of an article published by SAGE Publications in Clinical Rehabilitation on 17 June 2018, available online: https://journals.sagepub.com/doi/abs/10.1177/0269215518780487en
dc.subjectAphasiaen
dc.subjectMeta-analysisen
dc.subjectSocial supporten
dc.subjectRehabilitationen
dc.subjectStrokeen
dc.titleAttention control comparisons with SLT for people with aphasia following stroke: methodological concerns raised following a systematic reviewen
dc.typeArticle (peer-reviewed)en
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