The changing phenotype of Inflammatory Bowel Disease

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dc.contributor.authorMoran, Carthage
dc.contributor.authorSheehan, Donal
dc.contributor.authorShanahan, Fergus
dc.contributor.funderScience Foundation Irelanden
dc.date.accessioned2017-02-23T16:57:44Z
dc.date.available2017-02-23T16:57:44Z
dc.date.issued2016-11
dc.date.updated2017-02-23T16:40:16Z
dc.description.abstractIt is widely known that there have been improvements in patient care and an increased incidence of Inflammatory Bowel Disease (IBD) worldwide in recent decades. However, less well known are the phenotypic changes that have occurred; these are discussed in this review. Namely, we discuss the emergence of obesity in patients with IBD, elderly onset disease, mortality rates, colorectal cancer risk, the burden of medications and comorbidities, and the improvement in surgical treatment with a decrease in surgical rates in recent decades.en
dc.description.sponsorshipScience Foundation Ireland (Alimentary Pharmabiotic Centre Grants SFI/12/RC/2273 and 12/RC/2273)en
dc.description.statusNot peer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid1619053
dc.identifier.citationMoran, C., Sheehan, D. and Shanahan, F. (2016) 'The changing phenotype of Inflammatory Bowel Disease', Gastroenterology Research and Practice, 1619053 (9pp). doi: 10.1155/2016/1619053en
dc.identifier.doi10.1155/2016/1619053
dc.identifier.endpage9en
dc.identifier.issn1687-6121
dc.identifier.journaltitleGastroenterology Research and Practiceen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/3683
dc.language.isoenen
dc.publisherHindawi Publishing Corporationen
dc.rights© 2016, the Authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectBody-mass indexen
dc.subjectPopulation-based cohorten
dc.subjectPrimary sclerosing cholangitisen
dc.subjectCause-specific mortalityen
dc.subjectPouch-anal anastomosisen
dc.subjectUlcerative colitis dataen
dc.subjectCrohn's diseaseen
dc.titleThe changing phenotype of Inflammatory Bowel Diseaseen
dc.typeArticle (non peer-reviewed)en
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