A cost-effectiveness analysis of school-based suicide prevention programmes

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dc.contributor.authorAhern, Susan
dc.contributor.authorBurke, Lee-Ann
dc.contributor.authorMcElroy, Brendan
dc.contributor.authorCorcoran, Paul
dc.contributor.authorMcMahon, Elaine M.
dc.contributor.authorKeeley, Helen
dc.contributor.authorCarli, Vladimir
dc.contributor.authorWasserman, Camilla
dc.contributor.authorHoven, Christina W.
dc.contributor.authorSarchiapone, Marco
dc.contributor.authorApter, Alan
dc.contributor.authorBalazs, Judit
dc.contributor.authorBanzer, Raphaela
dc.contributor.authorBobes, Julio
dc.contributor.authorBrunner, Romuald
dc.contributor.authorCosman, Doina
dc.contributor.authorHaring, Christian
dc.contributor.authorKaess, Michael
dc.contributor.authorKahn, Jean-Pierre
dc.contributor.authorKereszteny, Agnes
dc.contributor.authorPostuvan, Vita
dc.contributor.authorSáiz, Pilar A.
dc.contributor.authorVarnik, Peeter
dc.contributor.authorWasserman, Danuta
dc.date.accessioned2018-03-13T15:34:19Z
dc.date.available2018-03-13T15:34:19Z
dc.date.issued2018-02-14
dc.description.abstractSuicide is one of the leading causes of death among young people globally. In light of emerging evidence supporting the effectiveness of school-based suicide prevention programmes, an analysis of cost-effectiveness is required. We aimed to conduct a full cost-effectiveness analysis (CEA) of the large pan-European school-based RCT, Saving and Empowering Young Lives in Europe (SEYLE). The health outcomes of interest were suicide attempt and severe suicidal ideation with suicide plans. Adopting a payer’s perspective, three suicide prevention interventions were modelled with a Control over a 12-month time period. Incremental cost-effectiveness ratios (ICERs) indicate that the Youth Aware of Mental Health (YAM) programme has the lowest incremental cost per 1% point reduction in incident for both outcomes and per quality adjusted life year (QALY) gained versus the Control. The ICERs reported for YAM were €34.83 and €45.42 per 1% point reduction in incident suicide attempt and incident severe suicidal ideation, respectively, and a cost per QALY gained of €47,017 for suicide attempt and €48,216 for severe suicidal ideation. Cost-effectiveness acceptability curves were used to examine uncertainty in the QALY analysis, where cost-effectiveness probabilities were calculated using net monetary benefit analysis incorporating a two-stage bootstrapping technique. For suicide attempt, the probability that YAM was cost-effective at a willingness to pay of €47,000 was 39%. For severe suicidal ideation, the probability that YAM was cost-effective at a willingness to pay of €48,000 was 43%. This CEA supports YAM as the most cost-effective of the SEYLE interventions in preventing both a suicide attempt and severe suicidal ideation. Trial registration number DRKS00000214.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAhern, S., Burke, L.-A., McElroy, B., Corcoran, P., McMahon, E. M., Keeley, H., Carli, V., Wasserman, C., Hoven, C. W., Sarchiapone, M., Apter, A., Balazs, J., Banzer, R., Bobes, J., Brunner, R., Cosman, D., Haring, C., Kaess, M., Kahn, J.-P., Kereszteny, A., Postuvan, V., Sáiz, P. A., Varnik, P. and Wasserman, D. (2018) 'A cost-effectiveness analysis of school-based suicide prevention programmes', European Child & Adolescent Psychiatry, 27, pp. 1295-1304, doi:10.1007/s00787-018-1120-5en
dc.identifier.doi10.1007/s00787-018-1120-5
dc.identifier.endpage10en
dc.identifier.endpage1304
dc.identifier.issn1435-165X
dc.identifier.journaltitleEuropean Child & Adolescent Psychiatryen
dc.identifier.startpage1en
dc.identifier.startpage1295
dc.identifier.urihttps://hdl.handle.net/10468/5621
dc.identifier.volume27
dc.language.isoenen
dc.publisherSpringer Verlagen
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::HEALTH/223091/EU/Saving and Empowering Young Lives in Europe: Promote health through prevention of risk-taking and self-destructive behaviors/SEYLEen
dc.rights© Springer-Verlag GmbH Germany, part of Springer Nature 2018. This is a post-peer-review, pre-copyedit version of an article published in European Child & Adolescent Psychiatry. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00787-018-1120-5en
dc.subjectSuicide attempten
dc.subjectSuicidal ideationen
dc.subjectPreventionen
dc.subjectInterventionen
dc.subjectAdolescentsen
dc.subjectSchoolen
dc.subjectCost-effectivenessen
dc.titleA cost-effectiveness analysis of school-based suicide prevention programmesen
dc.typeArticle (peer-reviewed)en
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