Reference centiles for infant sleep parameters from 4 to 16 weeks of age: findings from an Irish cohort

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dc.contributor.authorO'Sullivan, Marc Paulen
dc.contributor.authorLivingstone, Vickien
dc.contributor.authorKorotchikova, Irinaen
dc.contributor.authorDempsey, Eugene M.en
dc.contributor.authorMurray, Deirdre M.en
dc.contributor.authorBoylan, Geraldine B.en
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderJohnson and Johnsonen
dc.date.accessioned2023-05-09T14:17:03Z
dc.date.available2023-05-09T14:17:03Z
dc.date.issued2023-03-21en
dc.description.abstractObjectives: To establish unconditional reference centiles for sleep parameters in infants 4–16 weeks of age. Design and setting: Secondary data analysis of sleep parameters recorded at 4–16 weeks of age in a longitudinal randomised controlled trial (RCT) (BabySMART). Patients: Healthy term infants assigned to the non-intervention arm of the RCT. Main outcome measures: Infants’ sleep duration was recorded by parents/guardians daily, from week 2–16 of age using a sleep diary. Reference centiles for total, daytime, night-time and longest sleep episode duration were estimated using multilevel modelling. Results: One hundred and six infants, mean (SD) gestational age of 39.9 (1.2) weeks and mean (SD) birth weight of 3.6 (0.5) kg had sleep recorded contributing 1264 measurements for each sleep parameter. Between 4 and 16 weeks of age total sleep duration in a 24-hour period, night-time sleep duration in a 12-hour period and infant’s longest sleep episode duration increased, while daytime sleep duration in a 12-hour period decreased. Conclusions: Reference centiles up to 4 months of age in infants highlight the gradual decrease in daytime sleep and large increases in night-time sleep, which occur in tandem with increasing lengths of sleep episodes. These reference centiles provide useful sleep values for infant sleep trajectory occurring in early life and may be helpful for parents and clinicians.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationO'Sullivan, M.P., Livingstone, V., Korotchikova, I., Dempsey, E.M., Murray, D.M. and Boylan, G.B. (2023) ‘Reference centiles for infant sleep parameters from 4 to 16 weeks of age: findings from an Irish cohort’, Archives of Disease in Childhood, 108(6), pp. 481–485. https://doi.org/10.1136/archdischild-2022-324016.en
dc.identifier.doi10.1136/archdischild-2022-324016en
dc.identifier.eissn1468-2044en
dc.identifier.issn0003-9888en
dc.identifier.journaltitleArchives of Disease in Childhooden
dc.identifier.urihttps://hdl.handle.net/10468/14442
dc.language.isoenen
dc.publisherBMJ Publishing Group Ltd & Royal College of Paediatrics and Child Healthen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Spokes Programme/15/SP/3091/IE/ENRICH: Baby Enrichment Research Programme/en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2272/IE/Irish Centre for Fetal and Neonatal Translational Research (INFANT)/en
dc.rights© 2023, the Authors. Published by BMJ Publishing Group Ltd. This article has been accepted for publication in Archives of Disease in Childhood. The Version of Record can be accessed online at: https://dx.doi.org/10.1136/archdischild-2022-324016 No commercial re-use.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectInfanten
dc.subjectSleepen
dc.subjectDevelopmenten
dc.subjectSleep durationen
dc.titleReference centiles for infant sleep parameters from 4 to 16 weeks of age: findings from an Irish cohorten
dc.typeArticle (peer-reviewed)en
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