Screening canine sources for novel antimicrobials reveals the circular broad-spectrum bacteriocin, caledonicin, produced by Staphylococcus caledonicus
Loading...
Files
Published Version
Supplementary table S2
Supplementary table S2
Date
2024-08-26
Authors
O'Connor, Michelle
O'Connor, Paula M.
Hourigan, David
Murray, Ellen
de Farias, Felipe Miceli
Field, Des
Hill, Colin
Ross, R. Paul
Journal Title
Journal ISSN
Volume Title
Publisher
Frontiers Media S.A.
Published Version
Abstract
Antimicrobial-resistant pathogens present an ongoing threat to human and animal health, with deaths linked to antimicrobial resistance (AMR) predicted to increase annually. While the misuse and overuse of antibiotics in humans undoubtedly contribute to this escalation, antibiotic use in the veterinary field, including companion animals, also plays a contributing role. Pet owners’ desire to improve the quality of life of their pets is likely to support antibiotic use in this field. Consequently, there is a need for antibiotic alternatives to treat bacterial infections. This study set out to screen for antimicrobial peptides known as bacteriocins from bacterial isolates of aerobic/microaerophilic environments of canine sources and determine their potential as antibiotic alternatives against clinically relevant pathogens.
Description
Keywords
Antimicrobial resistance , Canine microbiota , Bacteriocins , Canine sources , Antimicrobial potential , Antimicrobial peptides , ~Microbiology - Journal Articles~
Citation
O'Connor, M., O’Connor, P.M., Hourigan, D., Murray, E., De Farias, F.M., Field, D., Hill, C. and Ross, R.P. (2024) ‘Screening canine sources for novel antimicrobials reveals the circular broad-spectrum bacteriocin, caledonicin, produced by Staphylococcus caledonicus’, Frontiers in Microbiology, 15, 1470988 (19pp). https://doi.org/10.3389/fmicb.2024.1470988