The effect of dietary supplementation with spent cider yeast on the swine distal gut microbiome

Show simple item record

dc.contributor.author Upadrasta, Aditya
dc.contributor.author O'Sullivan, Lisa
dc.contributor.author O'Sullivan, Orla
dc.contributor.author Sexton, Noel
dc.contributor.author Lawlor, Peadar G.
dc.contributor.author Hill, Colin
dc.contributor.author Fitzgerald, Gerald F.
dc.contributor.author Stanton, Catherine
dc.contributor.author Ross, R. Paul
dc.date.accessioned 2016-02-17T11:45:32Z
dc.date.available 2016-02-17T11:45:32Z
dc.date.issued 2013
dc.identifier.citation Upadrasta A, O’Sullivan L, O’Sullivan O, Sexton N, Lawlor PG, Hill C, et al. (2013) The Effect of Dietary Supplementation with Spent Cider Yeast on the Swine Distal Gut Microbiome. PLoS ONE 8(10): e75714. doi:10.1371/journal.pone.0075714
dc.identifier.volume 8 en
dc.identifier.issued 10 en
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/10468/2363
dc.identifier.doi 10.1371/journal.pone.0075714
dc.description.abstract Background: There is an increasing need for alternatives to antibiotics for promoting animal health, given the increasing problems associated with antibiotic resistance. In this regard, we evaluated spent cider yeast as a potential probiotic for modifying the gut microbiota in weanling pigs using pyrosequencing of 16S rRNA gene libraries. Methodology and Principal Findings: Piglets aged 24-26 days were assigned to one of two study groups; control (n = 12) and treatment (n = 12). The control animals were fed with a basal diet and the treatment animals were fed with basal diet in combination with cider yeast supplement (500 ml cider yeast containing similar to ∼7.6 log CFU/ml) for 21 days. Faecal samples were collected for 16s rRNA gene compositional analysis. 16S rRNA compositional sequencing analysis of the faecal samples collected from day 0 and day 21 revealed marked differences in microbial diversity at both the phylum and genus levels between the control and treatment groups. This analysis confirmed that levels of Salmonella and Escherichia were significantly decreased in the treatment group, compared with the control (P<0.001). This data suggest a positive influence of dietary supplementation with live cider yeast on the microbial diversity of the pig distal gut. Conclusions/Significance: The effect of dietary cider yeast on porcine gut microbial communities was characterized for the first time using 16S rRNA gene compositional sequencing. Dietary cider yeast can potentially alter the gut microbiota, however such changes depend on their endogenous microbiota that causes a divergence in relative response to that given diet. en
dc.description.sponsorship Enterprise Ireland (Commercialisation Fund CFTD/05/117); European Commission (European Research and Development Fund) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Public Library of Science en
dc.rights © 2015 Upadrasta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited en
dc.rights.uri http://creativecommons.org/licenses/by/4.0/ en
dc.subject Porcine gastrointestinal tract en
dc.subject Weanling pigs en
dc.subject Nutrient digestibility en
dc.subject High-throughput en
dc.subject Live yeast en
dc.subject Sp. nov. en
dc.subject Performance en
dc.subject Salmonella en
dc.subject Bacteria en
dc.subject Culture en
dc.title The effect of dietary supplementation with spent cider yeast on the swine distal gut microbiome en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Colin Hill, Microbiology, University College Cork, Cork, Ireland. +353-21-490-3000 Email: c.hill@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.internal.wokid WOS:000325810900054
dc.contributor.funder Enterprise Ireland
dc.contributor.funder Science Foundation Ireland
dc.contributor.funder European Commission
dc.description.status Peer reviewed en
dc.identifier.journaltitle PLOS ONE en
dc.internal.IRISemailaddress c.hill@ucc.ie en
dc.identifier.articleid e75714


Files in this item

This item appears in the following Collection(s)

Show simple item record

© 2015 Upadrasta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Except where otherwise noted, this item's license is described as © 2015 Upadrasta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
This website uses cookies. By using this website, you consent to the use of cookies in accordance with the UCC Privacy and Cookies Statement. For more information about cookies and how you can disable them, visit our Privacy and Cookies statement