Asymmetric oxidation of sulfides

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Date
2012-10-16
Authors
O'Mahony, Graham E.
Ford, Alan
Maguire, Anita R.
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Taylor and Francis
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Abstract
This review discusses synthesis of enantiopure sulfoxides through the asymmetric oxidation of prochiral sulfides. The use of metal complexes to promote asymmetric sulfoxidation is described in detail, with a particular emphasis on the synthesis of biologically active sulfoxides. The use of non-metal-based systems, such as oxaziridines, chiral hydroperoxides and peracids, as well as enzyme-catalyzed sulfoxidations is also examined.
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Keywords
Sulfide oxidation , Sulfoxides , Asymmetric synthesis , Enantioselective synthesis , Metal-based catalysts , Alkyl aryl sulfides , Chiral schiff-bases , Helminthosporium species NRRL-4671 , Optically-active sulfoxides , Benzyl methyl sulfoxides , Aqueous hydrogen-peroxide , Tert-butyl hydroperoxide , Twin coronet porphyrins , Mandelic-acid complex , Bovine serum-albumin
Citation
O'Mahony, G. E., Ford, A. and Maguire, A. R. (2013) 'Asymmetric oxidation of sulfides'. Journal of Sulfur Chemistry, 34(3), pp. 301-341. http://dx.doi.org/10.1080/17415993.2012.725247
Copyright
© 2013 Taylor and Francis Group, LLC. This is a Submitted Manuscript of an article published by Taylor & Francis in Journal of Sulfur Chemistry on 16 Oct 2012, available online: http://www.tandfonline.com/10.1080/17415993.2012.725247.