Finding the needle in the haystack: systematic identification of psychobiotics

Show simple item record Bambury, Aisling Sandhu, Kiran V. Cryan, John F. Dinan, Timothy G. 2018-01-09T12:50:08Z 2018-01-09T12:50:08Z 2017-12-15
dc.identifier.citation Bambury, A., Sandhu, K., Cryan, J. F. and Dinan, T. G. 'Finding the needle in the haystack: systematic identification of psychobiotics', British Journal of Pharmacology, In Press, doi: 10.1111/bph.14127 en
dc.identifier.startpage 1 en
dc.identifier.endpage 21 en
dc.identifier.issn 1476-5381
dc.identifier.doi 10.1111/bph.14127
dc.description.abstract The brain-gut-microbiota axis is increasingly viewed as a novel paradigm in neuroscience with the capacity to generate innovative therapies for patients with psychiatric illnesses. Psychobiotics, defined as live bacteria which when ingested in adequate amounts confer mental health benefits, are increasingly of interest, as pre-clinical trials continue to show promising results. Particularly in stress related, anxiety and depressive disorders, there is potential for psychobiotics to deliver new therapies. The question of which microbes may prove to be the most promising psychobiotic in delivering such therapies at clinical level is of great importance. Here we look at the characteristics of psychobiotics, in an attempt to present an outline, from which the identification of potential new psychobiotics may be possible. en
dc.description.sponsorship Health Research Board (Grant Numbers HRA_POR/2011/23 and HRA_POR/2012/32) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Wiley en
dc.rights © 2017 The British Pharmacological Society. Published by Wiley. This is the peer reviewed version of the following article: Bambury, A., Sandhu, K., Cryan, J. F., and Dinan, T. G. (2017) Finding the needle in the haystack: systematic identification of psychobiotics. British Journal of Pharmacology, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. en
dc.subject Brain-gut-microbiota axis en
dc.subject Psychobiotics en
dc.subject Psychiatric illness en
dc.subject Neuroscience en
dc.subject Stress en
dc.subject Depressive disorders en
dc.title Finding the needle in the haystack: systematic identification of psychobiotics en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Ted Dinan, Psychiatry, University College Cork, Cork, Ireland. +353-21-490-3000 Email: en
dc.internal.availability Full text available en Access to this article is restricted until 12 months after publication by request of the publisher. en 2018-12-15 2018-01-09T12:33:05Z
dc.description.version Accepted Version en
dc.internal.rssid 421115536
dc.contributor.funder Science Foundation Ireland en
dc.contributor.funder Health Research Board en
dc.contributor.funder Seventh Framework Programme en
dc.contributor.funder European Commission en
dc.description.status Peer reviewed en
dc.identifier.journaltitle British Journal of Pharmacology en
dc.internal.copyrightchecked No !!CORA!! en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress en
dc.relation.project info:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/ en
dc.relation.project info:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/613979/EU/Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior./MYNEWGUT en

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