Low-dose carotid computed tomography angiography using pure iterative reconstruction
Moloney, Fiachra; Murphy, Kevin P.; Twomey, Maria; Crish, Lee; Canniffe, Emma M.; McLaughlin, Patrick D.; Moore, Niamh; O'Keefe, Michael; O'Neill, Siobhán B.; Manning, Brian M.; Wyse, Gerald; Fanning, Noel; O'Connor, Owen J.; Maher, Michael M.
Date:
2016-09
Copyright:
© 2016 Wolters Kluwer Health, Inc. All rights reserved.
Citation:
Moloney, F., Murphy, K. P., Twomey, M., Crush, L., Canniffe, E. M., McLaughlin, P. D., Moore, N., O'Keeffe, M., O'Neill, S., Manning, B. M., Wyse, G., Fanning, N., O'Connor, O. J. and Maher, M. M. (2016) 'Low-Dose Carotid Computed Tomography Angiography Using Pure Iterative Reconstruction', Journal of Computer Assisted Tomography, 40(5), pp. 833-839. doi: 10.1097/RCT.0000000000000436
Abstract:
The aim of this study was to assess if a low-dose carotid computed tomography angiography (CTA) performed with pure iterative reconstruction (IR) is comparable to a conventional dose CTA protocol. Methods: Twenty patients were included. Radiation dose was divided into a low-dose acquisition reconstructed with pure IR and a conventional dose acquisition reconstructed with 40% hybrid IR. Dose, image noise, contrast resolution, spatial resolution, and carotid artery stenosis were measured. Results: Mean effective dose was significantly lower for low-dose than conventional dose studies (1.84 versus 3.71 mSv; P < 0.001). Subjective image noise, contrast resolution, and spatial resolution were significantly higher for the low-dose studies. There was excellent agreement for stenosis grading accuracy between low- and conventional dose studies (Cohen κ = 0.806). Conclusions: A low-dose carotid CTA protocol reconstructed with pure IR is comparable to a conventional dose CTA protocol in terms of image quality and diagnostic accuracy while enabling a dose reduction of 49.6%.
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