Association of fish intake and smoking with risk of rheumatoid arthritis and age of onset: a prospective cohort study

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s12891-018-2381-3.pdf(762.65 KB)
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Date
2019-01
Authors
Sparks, Jeffrey A.
O'Reilly, Éilis J.
Barbhaiya, Medha
Tedeschi, Sara K.
Malspeis, Susan
Lu, Bing
Willett, Walter C.
Costenbader, Karen H.
Karlson, Elizabeth W.
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BMC Part of Springer Nature
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Abstract
Prior studies suggest that fish may be protective for rheumatoid arthritis (RA) risk perhaps through the anti-inflammatory effect of omega-3 fatty acid, but this relationship has not been clearly established. Therefore, we investigated fish intake and RA risk by serologic status, age of onset, and smoking using a prospective cohort study with large sample size, repeated measures of dietary intake, and lengthy follow-up.
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Keywords
Rheumatoid arthritis , Fish , Diet , Inflammation , Omega-3 fatty acids , Smoking , Epidemiology
Citation
Sparks, J.A., O’Reilly, É.J., Barbhaiya, M., Tedeschi, S.K., Malspeis, S., Lu, B., Willett, W.C., Costenbader, K.H. and Karlson, E.W., 2019. Association of fish intake and smoking with risk of rheumatoid arthritis and age of onset: a prospective cohort study. BMC musculoskeletal disorders, 20:2, (13pp.) DOI: 10.1186/s12891-018-2381-3