Prescriber adherence to antihypertensive prescription guidelines and the impact of patient socioeconomic factors: a cross‐sectional study using data from the irish longitudinal study on ageing

Simple item page
dc.contributor.authorAkhtar, Alizehen
dc.contributor.authorBurton, Edelen
dc.contributor.authorBermingham, Margareten
dc.contributor.authorKearney, Patricia M.en
dc.contributor.funderIrish Research eLibraryen
dc.date.accessioned2024-11-04T11:52:36Z
dc.date.available2024-11-04T11:52:36Z
dc.date.issued2024en
dc.description.abstractPurpose Uncontrolled hypertension causes significant morbidity and mortality worldwide. Several prescribing guidelines have been created to address this, however, prescriber adherence to guidelines is influenced by various sociodemographic patient factors. This study aims to determine the effects of these patient factors on prescriber adherence to antihypertensive prescription guidelines. Methods A secondary analysis of data from the first wave of The Irish Longitudinal Study on Ageing (TILDA), was conducted. Participants were included if they reported previous hypertension diagnoses. Antihypertensive medication regimes were compared with the prescribing guidance in the 2011 NICE hypertension guidelines. The effects of patient sociodemographic factors on prescriber adherence to guidelines, and the effect of prescriber adherence on blood pressure control (≥ 140/90 mmHg), were determined using binomial logistic regression models. Results A total of 2992 participants were included in this analysis; 54.9% female with mean age 65.7 years (±9.23). Male sex and older age, and lower socioeconomic status were associated with increased prescriber guideline adherence. Prescribers were less likely to adhere to guidelines in female patients ≥ 55 years (Relative Risk [RR] 0.75 [0.62, 0.91]), and female patients across all age groups (RR 0.80 [0.67, 0.95]). Better blood pressure control was seen with medication regimes adherent to prescription guidelines (140.38 (±18.98)/83.09 (±11.02) mmHg adherent vs. 141.66 (±19.86)/84.77 (±11.71) mmHg non-adherent). Conclusions This study highlights the effect of patient sex on prescriber adherence to antihypertensive prescription guidelines, emphasizing a larger issue of systemic undertreatment of females observed within healthcare. Further research is needed to determine the reasons for such differences in hypertensive care.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide70025en
dc.identifier.citationAkhtar, A., Burton, E., Bermingham, M. and Kearney, P.M. (2024) ‘Prescriber adherence to antihypertensive prescription guidelines and the impact of patient socioeconomic factors: a cross‐sectional study using data from the irish longitudinal study on ageing’, Pharmacoepidemiology and Drug Safety, 33(11), e70025 (12pp). https://doi.org/10.1002/pds.70025en
dc.identifier.doihttps://doi.org/10.1002/pds.70025en
dc.identifier.eissn1099-1557en
dc.identifier.endpage12en
dc.identifier.issn1053-8569en
dc.identifier.issued11en
dc.identifier.journaltitlePharmacoepidemiology and Drug Safetyen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/16610
dc.identifier.volume33en
dc.language.isoenen
dc.publisherWileyen
dc.rights© 2024 The Author(s). Pharmacoepidemiology and Drug Safety published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the originalwork is properly cited, the use is non-commercial and no modifications or adaptations are madeen
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectAntihypertensive agentsen
dc.subjectGuideline adherenceen
dc.subjectHypertensionen
dc.subjectPrescribingen
dc.subjectSociodemographic factorsen
dc.titlePrescriber adherence to antihypertensive prescription guidelines and the impact of patient socioeconomic factors: a cross‐sectional study using data from the irish longitudinal study on ageingen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Pharmacoepidemiology and Drug - 2024 - Akhtar - Prescriber Adherence to Antihypertensive Prescription Guidelines and the.pdf
Size:
479.46 KB
Format:
Adobe Portable Document Format
Description:
Published Version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Public Health - Journal Articles
Medicine - Journal Articles
Pharmacy - Journal Articles