What do patients value as incentives for participation in clinical trials? A pilot discrete choice experiment

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dc.contributor.authorVellinga, Akke
dc.contributor.authorDevine, Colum
dc.contributor.authorHo, Min Yun
dc.contributor.authorClarke, Colin
dc.contributor.authorLeahy, Patrick
dc.contributor.authorBourke, Jane
dc.contributor.authorDevane, Declan
dc.contributor.authorDuane, Sinead
dc.contributor.authorKearney, Patricia
dc.date.accessioned2023-01-03T10:40:36Z
dc.date.available2023-01-03T10:40:36Z
dc.date.issued2020-01-21
dc.date.updated2022-12-21T12:34:36Z
dc.description.abstractIncentivising has shown to improve participation in clinical trials. However, ethical concerns suggest that incentives may be coercive, obscure trial risks and encourage individuals to enrol in clinical trials for the wrong reasons. The aim of our study was to develop and pilot a discrete choice experiment (DCE) to explore and identify preferences for incentives. A DCE was designed by including following attributes (and levels) of incentives: value, method, and time involvement. To account for trial benefit and risk, each was included as an attribute with levels low, medium and high. For testing purposes, the DCE was administrated using SurveyMonkey in a population of third level students. A total of 245 students, representative of the general student population, participated in the online DCE. The results provide a template to assess and explore the use of different incentive methods in clinical trials. The template can be used in its current format or adapted to particular scenarios. This pilot study provides a feasible methodology to explore the use of incentives for participation in clinical trials and can be adapted to specific trial requirements to provide information for ethical applications or identify the most favourable incentive for participation in clinical trials.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationVellinga, A., Devine, C., Ho, M. Y., Clarke, C., Leahy, P., Bourke, J., Devane, D., Duane, S. and Kearney, P. (2020) 'What do patients value as incentives for participation in clinical trials? A pilot discrete choice experiment', Research Ethics, 16(1-2), pp. 1-12. doi: 10.1177/1747016119898669en
dc.identifier.doi10.1177/1747016119898669en
dc.identifier.eissn2047-6094
dc.identifier.endpage12en
dc.identifier.issn1747-0161
dc.identifier.issued1-2en
dc.identifier.journaltitleResearch Ethicsen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/14003
dc.identifier.volume16en
dc.language.isoenen
dc.publisherSAGE Publicationsen
dc.rights© 2020, the Authors. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectDiscrete choice experimenten
dc.subjectIncentiveen
dc.subjectRandomised controlled trialen
dc.titleWhat do patients value as incentives for participation in clinical trials? A pilot discrete choice experimenten
dc.typeArticle (peer-reviewed)en
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