Health-related quality of life in women after colposcopy: results from a longitudinal patient survey

O'Connor, Mairead; Ó Céilleachair, A.; O'Brien, K.; O'Leary, J.; Martin, C.; D'Arcy, T.; Flannelly, G.; McRae, J.; Prendiville, W.; Ruttle, C.; White, C.; Pilkington, L.; Sharp, L.

Access to this article is restricted until 12 months after publication by request of the publisher.. Restriction lift date: 2022-04-01

Health-related quality of life in women after colposcopy: results from a longitudinal patient survey

Simple item page

dc.check.date	2022-04-01
dc.check.info	Access to this article is restricted until 12 months after publication by request of the publisher.	en
dc.contributor.author	O'Connor, Mairead
dc.contributor.author	Ó Céilleachair, A.
dc.contributor.author	O'Brien, K.
dc.contributor.author	O'Leary, J.
dc.contributor.author	Martin, C.
dc.contributor.author	D'Arcy, T.
dc.contributor.author	Flannelly, G.
dc.contributor.author	McRae, J.
dc.contributor.author	Prendiville, W.
dc.contributor.author	Ruttle, C.
dc.contributor.author	White, C.
dc.contributor.author	Pilkington, L.
dc.contributor.author	Sharp, L.
dc.contributor.funder	Health Research Board	en
dc.date.accessioned	2021-05-04T10:17:11Z
dc.date.available	2021-05-04T10:17:11Z
dc.date.issued	2021-04-01
dc.date.updated	2021-05-04T10:04:27Z
dc.description.abstract	Background: Information concerning the health-related quality-of-life (HRQoL) consequences of colposcopy is limited, particularly over time. In a longitudinal study, we investigated women’s HRQoL at 4, 8 and 12 months post colposcopy and the factors associated with this. Methods: Women attending colposcopy at two large hospitals affiliated with the national screening programme in Ireland were invited to complete questionnaires at 4, 8 and 12 months post colposcopy. HRQoL was measured using the EQ-5D-3L and compared across a range of socio-demographic, clinical and attitudinal variables. A mixed-effects logistic multivariable model was employed to investigate associations between these variables and low HRQoL. Results: Of 584 women initially recruited, 429, 343 and 303 completed questionnaires at 4, 8 and 12 months, respectively. The mean overall HRQoL score for the sample across all time points was 0.90 (SD 0.16). Approximately 18% of women experienced low HRQoL at each of the three time points. In multivariable testing, over the entire 12-month follow-up period, non-Irish nationals (OR 8.99, 95% CI 2.35–34.43) and women with high-grade referral cytology (OR 2.78, 95% CI 1.08–7.13) were at higher odds of low HRQoL. Women who were past (OR 0.20, 95% CI 0.07–0.58) or never (OR 0.42, 95% CI 0.16–1.12) smokers were at lower odds of low HRQoL than current smokers. As women’s satisfaction with their healthcare increased their odds of experiencing low HRQoL fell (OR per unit increase 0.51, 95% CI 0.34–0.75). Conclusions: Women’s HRQoL did not change over the 12 months post colposcopy, but some subgroups of women were at higher risk of experiencing low HRQoL. These subgroups may benefit from additional support.	en
dc.description.sponsorship	Health Research Board (HS-05–09; ICE 2011/2; ICE 2015–1037; HRA-HSR/2012/30; HRA-HSR/2012/30)	en
dc.description.status	Peer reviewed	en
dc.description.version	Accepted Version	en
dc.format.mimetype	application/pdf	en
dc.identifier.citation	O'Connor, M., Ó Céilleachair, A., O'Brien, K., O'Leary, J., Martin, C., D'Arcy, T., Flannelly, G., McRae, J., Prendiville, W., Ruttle, C., White, C., Pilkington, L. and Sharp, L. (2021) 'Health-related quality of life in women after colposcopy: results from a longitudinal patient survey', Quality of Life Research. doi: 10.1007/s11136-021-02831-3	en
dc.identifier.doi	10.1007/s11136-021-02831-3	en
dc.identifier.eissn	1573-2649
dc.identifier.issn	0962-9343
dc.identifier.journaltitle	Quality of Life Research	en
dc.identifier.uri	https://hdl.handle.net/10468/11244
dc.language.iso	en	en
dc.publisher	Springer Nature Switzerland AG	en
dc.rights	© 2021, the Authors, under exclusive licence to Springer Nature Switzerland AG, part of Springer Nature. This is a post-peer-review, pre-copyedit version of an article published in Quality of Life Research. The final authenticated version is available online at: https://doi.org/10.1007/s11136-021-02831-3	en
dc.subject	Health-related quality of life	en
dc.subject	Colposcopy	en
dc.subject	Cervical screening	en
dc.subject	Longitudinal study design	en
dc.title	Health-related quality of life in women after colposcopy: results from a longitudinal patient survey	en
dc.type	Article (peer-reviewed)	en