Asymmetric oxidation of sulfides
O'Mahony, Graham E.
Maguire, Anita R.
Taylor and Francis
This review discusses synthesis of enantiopure sulfoxides through the asymmetric oxidation of prochiral sulfides. The use of metal complexes to promote asymmetric sulfoxidation is described in detail, with a particular emphasis on the synthesis of biologically active sulfoxides. The use of non-metal-based systems, such as oxaziridines, chiral hydroperoxides and peracids, as well as enzyme-catalyzed sulfoxidations is also examined.
Sulfide oxidation , Sulfoxides , Asymmetric synthesis , Enantioselective synthesis , Metal-based catalysts , Alkyl aryl sulfides , Chiral schiff-bases , Helminthosporium species NRRL-4671 , Optically-active sulfoxides , Benzyl methyl sulfoxides , Aqueous hydrogen-peroxide , Tert-butyl hydroperoxide , Twin coronet porphyrins , Mandelic-acid complex , Bovine serum-albumin
O'Mahony, G. E., Ford, A. and Maguire, A. R. (2013) 'Asymmetric oxidation of sulfides'. Journal of Sulfur Chemistry, 34(3), pp. 301-341. http://dx.doi.org/10.1080/17415993.2012.725247
© 2013 Taylor and Francis Group, LLC. This is a Submitted Manuscript of an article published by Taylor & Francis in Journal of Sulfur Chemistry on 16 Oct 2012, available online: http://www.tandfonline.com/10.1080/17415993.2012.725247.