Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial.
| dc.contributor.author | Brady, Paul | |
| dc.contributor.author | Iohom, Gabriella | |
| dc.contributor.author | O'Halloran, Ken D. | |
| dc.contributor.author | McCreary, Christine | |
| dc.contributor.author | Cronin, Michael | |
| dc.contributor.funder | Health Research Board | en |
| dc.date.accessioned | 2019-11-29T11:42:23Z | |
| dc.date.available | 2019-11-29T11:42:23Z | |
| dc.date.issued | 2017-10-11 | |
| dc.date.updated | 2019-11-28T13:43:40Z | |
| dc.description.abstract | Objectives/Aims: There has been no dentistry-specific published data supporting the use of monitoring with capnography for dental sedation. Our aim was to determine if adding capnography to standard monitoring during conscious sedation with midazolam would decrease the incidence of hypoxaemia. Materials and Methods: A randomised controlled trial was conducted in which all patients (ASA I and II) received standard monitoring and capnography, but were randomised to whether staff could view the capnography (intervention) or were blinded to it (control). The primary outcome was the incidence of hypoxaemia (SpO2⩽94%). Results: We enrolled 190 patients, mean age 31 years (range, 14–62 years). There were 93 patients in the capnography group and 97 in the control group. The mean cumulative dose of midazolam titrated was 6.94 mg (s.d., 2.31; range, 3–20 mg). Six (3%) patients, three in each group, required temporary supplemental oxygen. There was no statistically significant difference between the capnography and control groups for the incidence of hypoxaemia: 34.4 vs 39.2% (P=0.4962, OR=0.81, 95% CI: 0.45–1.47). Conclusions: We were unable to confirm an additive role for capnography to prevent hypoxaemia during conscious sedation with midazolam for patients not routinely administered supplemental oxygen. | en |
| dc.description.sponsorship | Health Research Board, Ireland (grant number HPF-2013-458 | en |
| dc.description.status | Peer reviewed | en |
| dc.description.version | Published Version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.articleid | 17019 | en |
| dc.identifier.citation | Brady, P., Iohom, G., O’Halloran, K. D., McCreary, C. and Cronin, M. (2017) 'Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial', BDJ Open, 3(1), 17019 (5 pp). doi: 10.1038/bdjopen.2017.19 | en |
| dc.identifier.doi | 10.1038/bdjopen.2017.19 | en |
| dc.identifier.endpage | 5 | en |
| dc.identifier.issn | 2056-807X | |
| dc.identifier.journaltitle | Bdj Open | en |
| dc.identifier.startpage | 1 | en |
| dc.identifier.uri | https://hdl.handle.net/10468/9281 | |
| dc.identifier.volume | 3 | en |
| dc.language.iso | en | en |
| dc.publisher | Springer Nature | en |
| dc.relation.uri | https://www.nature.com/articles/bdjopen201719 | |
| dc.rights | © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | en |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en |
| dc.subject | Sedation | en |
| dc.subject | Dental sedation | en |
| dc.subject | Capnography | en |
| dc.subject | Conscious Sedation | en |
| dc.subject | hypoxaemia | en |
| dc.title | Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial. | en |
| dc.type | Article (peer-reviewed) | en |
