Gold octahedra nanoparticles (Au_0.03 and Au_0.045): Synthesis and impact on marine clams Ruditapes decussatus

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dc.contributor.author Fkiri, Anis
dc.contributor.author Sellami, Badreddine
dc.contributor.author Selmi, Aymen
dc.contributor.author Khazri, Abdelhafidh
dc.contributor.author Saidani, Wiem
dc.contributor.author Imen, Bouzidi
dc.contributor.author Sheehan, David
dc.contributor.author Hamouda, Beyrem
dc.contributor.author Smiri, Leila Samia
dc.date.accessioned 2018-10-11T14:07:27Z
dc.date.available 2018-10-11T14:07:27Z
dc.date.issued 2018-07-05
dc.identifier.citation Fkiri, A., Sellami, B., Selmi, A., Khazri, A., Saidani, W., Imen, B., Sheehan, D., Hamouda, B. and Smiri, L. S. (2018) 'Gold Octahedra nanoparticles (Au_0.03 and Au_0.045): Synthesis and impact on marine clams Ruditapes decussatus', Aquatic Toxicology, 202, pp. 97-104. doi: 10.1016/j.aquatox.2018.07.004 en
dc.identifier.volume 202 en
dc.identifier.startpage 97 en
dc.identifier.endpage 104 en
dc.identifier.issn 0166-445X
dc.identifier.uri http://hdl.handle.net/10468/7000
dc.identifier.doi 10.1016/j.aquatox.2018.07.004
dc.description.abstract The increased use of gold nanoparticles (AuNPs) in several applications has led to a rise in concerns about their potential toxicity to aquatic organisms. In addition, toxicity of nanoparticles to aquatic organisms is related to their physical and chemical properties. In the present study, we synthesize two forms of gold octahedra nanoparticles (Au_0.03 and Au_0.045) in 1.3-propandiol with polyvinyl-pyrrolidone K30 (PVPK30) as capping agent using polyol process. Shape, size and optical properties of the particles could be tuned by changing the molar ratio of PVP K30 to metal salts. The anisotropy in nanoparticles shape shows strong localized surface plasmon resonance (SPR) in the near infrared region of the electromagnetic spectrum. Environmental impact of Oct-AuNPs was determined in the marine bivalve, Ruditapes decussatus exposed to different concentrations of Au_0.03 and Au_0.045. The dynamic light scattering showed the stability and resistance of Au_0.03 and Au_0.045 in the natural seawater. No significant modification in vg-like proteins, MDA level and enzymatic activities were observed in treated clams with Au_0.03 even at high concentration. In contrast, Au_0.045 induced superoxide dismutase (SOD), catalase (CAT), glutathione transferase (GST) activities, in a concentration dependent manner indicating defense against oxidative stress. Enhanced lipid peroxidation represented by malondialdehyde content confirmed oxidative stress of Au_0.045 at high concentration. These results highlight the importance of the physical form of nanomaterials on their interactions with marine organisms and provide a useful guideline for future use of Oct-AuNPs. In addition, Vitellogenin is shown not to be an appropriate biomarker for Oct-AuNPs contamination even at high concentration. We further show that Oct-AuNPs exhibit an important antioxidant response without inducing estrogenic disruption. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Elsevier en
dc.relation.uri http://www.sciencedirect.com/science/article/pii/S0166445X18304120
dc.rights © 2018 Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license. en
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/ en
dc.subject Gold nano-octahedra en
dc.subject Surface plasmon resonance en
dc.subject Ecotoxicology en
dc.subject Biomarkers en
dc.subject Biomonitoring en
dc.subject Oxidative stress en
dc.title Gold octahedra nanoparticles (Au_0.03 and Au_0.045): Synthesis and impact on marine clams Ruditapes decussatus en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother David Sheehan, School Of Biochemistry & Cell Biology, University College Cork, Cork, Ireland. +353-21-490-3000 Email: d.sheehan@ucc.ie en
dc.internal.availability Full text available en
dc.check.info Access to this article is restricted until 24 months after publication by request of the publisher. en
dc.check.date 2020-07-05
dc.description.version Accepted Version en
dc.contributor.funder Ministère de l'Enseignement Supérieur et de la Recherche Scientifique, Tunisie fr
dc.description.status Peer reviewed en
dc.identifier.journaltitle Aquatic Toxicology en
dc.internal.copyrightchecked !!CORA!! en
dc.internal.IRISemailaddress d.sheehan@ucc.ie en


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© 2018 Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license. Except where otherwise noted, this item's license is described as © 2018 Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license.
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