Bioaccessibility and bioavailability of a marine-derived multimineral, Aquamin-Magnesium
dc.contributor.author | Felice, Valeria D. | |
dc.contributor.author | O'Gorman, Denise M. | |
dc.contributor.author | O'Brien, Nora M. | |
dc.contributor.author | Hyland, Niall P. | |
dc.contributor.funder | Marigot Ltd | |
dc.contributor.funder | Irish Research Council | |
dc.contributor.funder | Science Foundation Ireland | |
dc.date.accessioned | 2018-09-27T12:08:19Z | |
dc.date.available | 2018-09-27T12:08:19Z | |
dc.date.issued | 2018 | |
dc.description.abstract | Introduction: Magnesium is an essential mineral involved in a range of key biochemical pathways. Several magnesium supplements are present on the market and their degree of bioavailability differs depending on the form of magnesium salt used. Aquamin-Mg is a natural source of magnesium, containing 72 additional trace minerals derived from the clean waters off the Irish coast. However, the in vitro bioaccessibility and bioavailability of Aquamin-Mg in comparison with other supplement sources of magnesium has yet to be tested. Method: Aquamin-Mg, magnesium chloride (MgCl2) and magnesium oxide (MgO) were subjected to gastrointestinal digestion according to the harmonized INFOGEST in vitro digestion method and in vitro bioavailability tested using the Caco-2 cell model. Magnesium concentration was measured by atomic absorption spectrophotometry (AAS). Results: Magnesium recovery from both Aquamin-Mg and MgCl2 was greater than for MgO. Magnesium from all three sources was transported across the epithelial monolayer with Aquamin-Mg displaying a comparable profile to the more bioavailable MgCl2. Conclusions: Our data support that magnesium derived from a marine-derived multimineral product is bioavailable to a significantly greater degree than MgO and displays a similar profile to the more bioavailable MgCl2 and may offer additional health benefits given its multimineral profile. | en |
dc.description.sponsorship | Irish Research Council (Enterprise Partnership Scheme Postdoctoral Fellowship, EPSPD/2015/52); | en |
dc.description.status | Peer reviewed | en |
dc.description.version | Published Version | en |
dc.format.mimetype | application/pdf | en |
dc.identifier.articleid | 912 | |
dc.identifier.citation | Felice, V., O’Gorman, D., O’Brien, N. and Hyland, N. (2018) 'Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium', Nutrients, 10(7), 912 (8pp). doi: 10.3390/nu10070912 | en |
dc.identifier.doi | 10.3390/nu10070912 | |
dc.identifier.endpage | 8 | |
dc.identifier.issn | 2072-6643 | |
dc.identifier.issued | 7 | |
dc.identifier.journaltitle | Nutrients | en |
dc.identifier.startpage | 1 | |
dc.identifier.uri | https://hdl.handle.net/10468/6935 | |
dc.identifier.volume | 10 | |
dc.language.iso | en | en |
dc.publisher | MDPI AG | en |
dc.relation.project | info:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/ | |
dc.relation.uri | http://www.mdpi.com/2072-6643/10/7/912 | |
dc.rights | © 2018, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Aquamin | en |
dc.subject | Multimineral supplement | en |
dc.subject | Magnesium bioavailability | en |
dc.title | Bioaccessibility and bioavailability of a marine-derived multimineral, Aquamin-Magnesium | en |
dc.type | Article (peer-reviewed) | en |
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