Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection

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Date
2019
Authors
Las Heras, Vanessa
Clooney, Adam G.
Ryan, Feargal J.
Cabrera-Rubio, Raul
Casey, Pat G.
Hueston, Cara M.
Pinheiro, Jorge
Rudkin, Justine K.
Melgar, Silvia
Cotter, Paul D.
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BioMed Central
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Abstract
A westernized diet comprising a high caloric intake from animal fats is known to influence the development of pathological inflammatory conditions. However, there has been relatively little focus upon the implications of such diets for the progression of infectious disease. Here, we investigated the influence of a high-fat (HF) diet upon parameters that influence Listeria monocytogenes infection in mice.
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Keywords
Diet , Infection , Microbiome , Listeria monocytogenes , Mice , Murine , Immunity , Goblet cell
Citation
Las Heras, V., Clooney, A. G., Ryan, F. J., Cabrera-Rubio, R., Casey, P. G., Hueston, C. M., Pinheiro, J., Rudkin, J. K., Melgar, S., Cotter, P. D., Hill, C. and Gahan, C. G. M. (2019) 'Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection', Microbiome, 7(1) (12pp). DOI: 10.1186/s40168-019-0621-x